Gliclazide

The crystal structure of gliclazide, N-[(perhydrocyclopenta [c]pyrrol-2-yl)aminocarbonyl]-p-toluenesulfonamide, C15H21B3O3S, a second-generation oral hypoglycemic agent, contains discrete molecules with normal molecular dimensions. Both of the five-membered fused rings adopt envelope conformations....

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Published in:Acta crystallographica. Section C, Crystal structure communications Crystal structure communications, 1999-01, Vol.55 (1), p.74-75
Main Authors: Parvez, M., Arayne, M. S., Zaman, M. K., Sultana, N.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Condensed matter: structure, mechanical and thermal properties
Crystallography, X-Ray
Exact sciences and technology
General and cellular metabolism. Vitamins
Gliclazide - chemistry
Heterocyclic compounds
Hypoglycemic Agents - chemistry
Medical sciences
Molecular Structure
Organic compounds
Pharmacology. Drug treatments
Physics
Structure of solids and liquids
crystallography
Structure of specific crystalline solids
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container_issue 1
container_start_page 74
container_title Acta crystallographica. Section C, Crystal structure communications
container_volume 55
creator Parvez, M.
Arayne, M. S.
Zaman, M. K.
Sultana, N.
description The crystal structure of gliclazide, N-[(perhydrocyclopenta [c]pyrrol-2-yl)aminocarbonyl]-p-toluenesulfonamide, C15H21B3O3S, a second-generation oral hypoglycemic agent, contains discrete molecules with normal molecular dimensions. Both of the five-membered fused rings adopt envelope conformations. The molecules are linked into chains by intermolecular hydrogen bonds involving amino-H atoms, with N...O separations of 2.967 (3) and 2.949 (3) A.
doi_str_mv 10.1107/S0108270198009883
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1600-5759
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source Wiley-Blackwell Read & Publish Collection
subjects Biological and medical sciences
Condensed matter: structure, mechanical and thermal properties
Crystallography, X-Ray
Exact sciences and technology
General and cellular metabolism. Vitamins
Gliclazide - chemistry
Heterocyclic compounds
Hypoglycemic Agents - chemistry
Medical sciences
Molecular Structure
Organic compounds
Pharmacology. Drug treatments
Physics
Structure of solids and liquids
crystallography
Structure of specific crystalline solids
title Gliclazide
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