Topical cidofovir for severe warts in a patient affected by AIDS and Hodgkin's lymphoma

We describe a 42-year-old man with AIDS and Hodgkin's lymphoma whose severe and recalcitrant cutaneous warts resolved following treatment with local 1% cidofovir. Clinically significant improvements were observed in a two-week period of therapy. In advanced HIV disease complicated by additional...

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Bibliographic Details
Published in:International journal of STD & AIDS 2008-10, Vol.19 (10), p.715-716
Main Authors: De Socio, G V L, Simonetti, S, Rosignoli, D, Minga, P, Tomassini, G M, Baldelli, F
Format: Article
Language:English
Subjects:
Administration, Topical
Adult
AIDS/HIV
Antiviral Agents - administration & dosage
Antiviral Agents - therapeutic use
Biological and medical sciences
Cytosine - administration & dosage
Cytosine - analogs & derivatives
Cytosine - therapeutic use
Foot
General aspects
Hand
HIV Infections - complications
Hodgkin Disease - complications
Human immunodeficiency virus
Human papillomavirus 16 - classification
Human papillomavirus 16 - genetics
Human papillomavirus 16 - isolation & purification
Human viral diseases
Humans
Infectious diseases
Lymphoma, AIDS-Related - complications
Male
Medical sciences
Organophosphonates - administration & dosage
Organophosphonates - therapeutic use
Papillomaviridae - classification
Papillomaviridae - drug effects
Papillomavirus
Treatment Outcome
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
Viral diseases with cutaneous or mucosal lesions and viral diseases of the eye
Warts - complications
Warts - drug therapy
Warts - virology
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Description
Summary:We describe a 42-year-old man with AIDS and Hodgkin's lymphoma whose severe and recalcitrant cutaneous warts resolved following treatment with local 1% cidofovir. Clinically significant improvements were observed in a two-week period of therapy. In advanced HIV disease complicated by additional haematological malignancy, cutaneous warts may be difficult to treat and present a challenge for the attending physicians. In similar clinical condition topical anti-human papillomavirus therapy may prove to be safe and curative.
ISSN:0956-4624
1758-1052
DOI:10.1258/ijsa.2008.008065