Lipodystrophia centrifugalis abdominalis infantilis in a Caucasian girl: report of a case with perieccrine inflammation

Lipodystrophia centrifugalis abdominalis infantilis (LCAI) is a rare, self‐limiting disease typically affecting Asian children around the age of three. In classic cases, patients present with a hypopigmented patch with central atrophy and an erythematous border in the groin area. We present a case o...

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Bibliographic Details
Published in:Journal of cutaneous pathology 2008-10, Vol.35 (10), p.971-974
Main Authors: Grande Sarpa, Hege, Vanderhooft, Sheryll, Bowen, Anneli R.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Child, Preschool
Dermatologic Agents
Dermatology
Eccrine Glands - pathology
European Continental Ancestry Group
Female
General aspects
Groin - pathology
Humans
Immunohistochemistry
Inflammation - drug therapy
Inflammation - pathology
Lipodystrophy - drug therapy
Lipodystrophy - metabolism
Lipodystrophy - pathology
Medical sciences
Skin - drug effects
Skin - pathology
Skin involvement in other diseases. Miscellaneous. General aspects
Tacrolimus - analogs & derivatives
Tacrolimus - therapeutic use
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Summary:Lipodystrophia centrifugalis abdominalis infantilis (LCAI) is a rare, self‐limiting disease typically affecting Asian children around the age of three. In classic cases, patients present with a hypopigmented patch with central atrophy and an erythematous border in the groin area. We present a case of LCAI affecting a female Caucasian toddler that shows striking perieccrine inflammation, a finding not previously reported in this entity. LCAI has been rarely reported in Caucasian children; as a result, there is sparse literature on the histopathological findings in this subset. This case illustrates how significant deep dermal and perieccrine inflammation can be seen in this condition, thus broadening the histopathological spectrum of this disorder.
ISSN:0303-6987
1600-0560
DOI:10.1111/j.1600-0560.2007.00942.x