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Antibiotic prescribing patterns and hospital admissions with respiratory and urinary tract infections
Objective To explore the relationship between antibiotic prescribing indicators for assessing the prescribing quality of general practitioners (GPs) and populations’ health outcome indicators. Design Descriptive cross-sectional study. Setting Aljarafe Primary Health Care Area (population 321,034) un...
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| Published in: | European journal of clinical pharmacology 2008-10, Vol.64 (10), p.1005-1011 |
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| container_title | European journal of clinical pharmacology |
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| creator | Fernández Urrusuno, Rocío Pedregal González, Miguel Torrecilla Rojas, Ma. Amparo |
| description | Objective
To explore the relationship between antibiotic prescribing indicators for assessing the prescribing quality of general practitioners (GPs) and populations’ health outcome indicators.
Design
Descriptive cross-sectional study.
Setting
Aljarafe Primary Health Care Area (population 321,034) under the administrative jurisdiction of the Andalusian Public Health Care Service, Spain. In total, 162 GPs, representing 95.29% of the total number of GPs in the study area, were included in the analysis.
Methods
Antibiotic prescribing indicators based on clinical evidence and recommendations from local resistance patterns were chosen by the consensus group technique. Hospital admissions due to respiratory tract and urinary infections in the three hospitals of the study area were recorded. Multiple regression analysis was carried out to determine the relationship between community prescribing of antibiotics and hospital admissions due to serious complications from respiratory and urinary infections.
Results
The higher prescribing of antibiotics adjusted for patients and working days was associated with a significantly higher number of adjusted hospital admissions due complications arising from respiratory and urinary infections (
p
|
| doi_str_mv | 10.1007/s00228-008-0514-6 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69620150</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>69620150</sourcerecordid><originalsourceid>FETCH-LOGICAL-c399t-36c46532bd8694e44bae2b5d93f487a06261ac5c22ee10d86d168765fcd39bea3</originalsourceid><addsrcrecordid>eNp1kU1LxDAQhoMouq7-AC9SBL1VJx9Nm-Oy-AULXvQc0jTdjXTTmqSI_96su7ggeAjJJM87M5kXoQsMtxigvAsAhFQ5QFoFZjk_QBPMKMkxMHyIJgAU51yUcIJOQ3gHwIUAeoxOcMWhLCoyQWbmoq1tH63OBm-C9ilyy2xQMRrvQqZck636MNioukw1axuC7dP9p42rLAkG61Xs_dcPOHrrVDpHr3TMrGuNjhv6DB21qgvmfLdP0dvD_ev8KV-8PD7PZ4tcUyFiTrlmvKCkbioumGGsVobURSNoy6pSASccK11oQozBkKAG86rkRasbKmqj6BTdbPMOvv8YTYgy9atN1yln-jFILjhJQ4AEXv0B3_vRu9SbJJixioqySBDeQtr3IXjTysHbdfqfxCA3BsitATIZIDcGSJ40l7vEY702zV6xm3gCrneAClp1rVdO2_DLESgZ4WxTnGy5kJ7c0vh9h_9X_wb7mp73</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>214483975</pqid></control><display><type>article</type><title>Antibiotic prescribing patterns and hospital admissions with respiratory and urinary tract infections</title><source>Springer Nature</source><creator>Fernández Urrusuno, Rocío ; Pedregal González, Miguel ; Torrecilla Rojas, Ma. Amparo</creator><creatorcontrib>Fernández Urrusuno, Rocío ; Pedregal González, Miguel ; Torrecilla Rojas, Ma. Amparo</creatorcontrib><description>Objective
To explore the relationship between antibiotic prescribing indicators for assessing the prescribing quality of general practitioners (GPs) and populations’ health outcome indicators.
Design
Descriptive cross-sectional study.
Setting
Aljarafe Primary Health Care Area (population 321,034) under the administrative jurisdiction of the Andalusian Public Health Care Service, Spain. In total, 162 GPs, representing 95.29% of the total number of GPs in the study area, were included in the analysis.
Methods
Antibiotic prescribing indicators based on clinical evidence and recommendations from local resistance patterns were chosen by the consensus group technique. Hospital admissions due to respiratory tract and urinary infections in the three hospitals of the study area were recorded. Multiple regression analysis was carried out to determine the relationship between community prescribing of antibiotics and hospital admissions due to serious complications from respiratory and urinary infections.
Results
The higher prescribing of antibiotics adjusted for patients and working days was associated with a significantly higher number of adjusted hospital admissions due complications arising from respiratory and urinary infections (
p
< 0.001) (
R
2
= 0.142). This relationship was not found for indicators based on the relative prescribing of recommended first-line versus second and third-line antibiotics. There were fewer patients of women GPs admitted to hospitals (
p
= 0.021).
Conclusions
Our findings show a statistically significant relationship—at the GPs level—between the quantitative antibiotic prescribing rate and standardized hospital admissions due to complications arising from respiratory and urinary infections of the assisted patients. Strategies should be addressed to reduce unnecessary antibiotic prescribing in primary care.</description><identifier>ISSN: 0031-6970</identifier><identifier>EISSN: 1432-1041</identifier><identifier>DOI: 10.1007/s00228-008-0514-6</identifier><identifier>PMID: 18607582</identifier><language>eng</language><publisher>Berlin/Heidelberg: Springer-Verlag</publisher><subject>Anti-Bacterial Agents - therapeutic use ; Antibiotics ; Bacterial diseases ; Bacterial diseases of the urinary system ; Biological and medical sciences ; Biomedical and Life Sciences ; Biomedicine ; Cross-Sectional Studies ; Drug Utilization ; Female ; Hospitalization - statistics & numerical data ; Human bacterial diseases ; Humans ; Infections ; Infectious diseases ; Male ; Medical sciences ; Middle Aged ; Nephrology. Urinary tract diseases ; Outcome Assessment (Health Care) ; Pharmacoepidemiology and Prescription ; Pharmacology. Drug treatments ; Pharmacology/Toxicology ; Physicians, Family - statistics & numerical data ; Prescriptions ; Primary care ; Respiratory diseases ; Respiratory Tract Infections - complications ; Respiratory Tract Infections - drug therapy ; Retrospective Studies ; Urinary system involvement in other diseases. Miscellaneous ; Urinary tract diseases ; Urinary Tract Infections - complications ; Urinary Tract Infections - drug therapy ; Urinary tract. Prostate gland</subject><ispartof>European journal of clinical pharmacology, 2008-10, Vol.64 (10), p.1005-1011</ispartof><rights>Springer-Verlag 2008</rights><rights>2008 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c399t-36c46532bd8694e44bae2b5d93f487a06261ac5c22ee10d86d168765fcd39bea3</citedby><cites>FETCH-LOGICAL-c399t-36c46532bd8694e44bae2b5d93f487a06261ac5c22ee10d86d168765fcd39bea3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20742645$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/18607582$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Fernández Urrusuno, Rocío</creatorcontrib><creatorcontrib>Pedregal González, Miguel</creatorcontrib><creatorcontrib>Torrecilla Rojas, Ma. Amparo</creatorcontrib><title>Antibiotic prescribing patterns and hospital admissions with respiratory and urinary tract infections</title><title>European journal of clinical pharmacology</title><addtitle>Eur J Clin Pharmacol</addtitle><addtitle>Eur J Clin Pharmacol</addtitle><description>Objective
To explore the relationship between antibiotic prescribing indicators for assessing the prescribing quality of general practitioners (GPs) and populations’ health outcome indicators.
Design
Descriptive cross-sectional study.
Setting
Aljarafe Primary Health Care Area (population 321,034) under the administrative jurisdiction of the Andalusian Public Health Care Service, Spain. In total, 162 GPs, representing 95.29% of the total number of GPs in the study area, were included in the analysis.
Methods
Antibiotic prescribing indicators based on clinical evidence and recommendations from local resistance patterns were chosen by the consensus group technique. Hospital admissions due to respiratory tract and urinary infections in the three hospitals of the study area were recorded. Multiple regression analysis was carried out to determine the relationship between community prescribing of antibiotics and hospital admissions due to serious complications from respiratory and urinary infections.
Results
The higher prescribing of antibiotics adjusted for patients and working days was associated with a significantly higher number of adjusted hospital admissions due complications arising from respiratory and urinary infections (
p
< 0.001) (
R
2
= 0.142). This relationship was not found for indicators based on the relative prescribing of recommended first-line versus second and third-line antibiotics. There were fewer patients of women GPs admitted to hospitals (
p
= 0.021).
Conclusions
Our findings show a statistically significant relationship—at the GPs level—between the quantitative antibiotic prescribing rate and standardized hospital admissions due to complications arising from respiratory and urinary infections of the assisted patients. Strategies should be addressed to reduce unnecessary antibiotic prescribing in primary care.</description><subject>Anti-Bacterial Agents - therapeutic use</subject><subject>Antibiotics</subject><subject>Bacterial diseases</subject><subject>Bacterial diseases of the urinary system</subject><subject>Biological and medical sciences</subject><subject>Biomedical and Life Sciences</subject><subject>Biomedicine</subject><subject>Cross-Sectional Studies</subject><subject>Drug Utilization</subject><subject>Female</subject><subject>Hospitalization - statistics & numerical data</subject><subject>Human bacterial diseases</subject><subject>Humans</subject><subject>Infections</subject><subject>Infectious diseases</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Nephrology. Urinary tract diseases</subject><subject>Outcome Assessment (Health Care)</subject><subject>Pharmacoepidemiology and Prescription</subject><subject>Pharmacology. Drug treatments</subject><subject>Pharmacology/Toxicology</subject><subject>Physicians, Family - statistics & numerical data</subject><subject>Prescriptions</subject><subject>Primary care</subject><subject>Respiratory diseases</subject><subject>Respiratory Tract Infections - complications</subject><subject>Respiratory Tract Infections - drug therapy</subject><subject>Retrospective Studies</subject><subject>Urinary system involvement in other diseases. Miscellaneous</subject><subject>Urinary tract diseases</subject><subject>Urinary Tract Infections - complications</subject><subject>Urinary Tract Infections - drug therapy</subject><subject>Urinary tract. Prostate gland</subject><issn>0031-6970</issn><issn>1432-1041</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><recordid>eNp1kU1LxDAQhoMouq7-AC9SBL1VJx9Nm-Oy-AULXvQc0jTdjXTTmqSI_96su7ggeAjJJM87M5kXoQsMtxigvAsAhFQ5QFoFZjk_QBPMKMkxMHyIJgAU51yUcIJOQ3gHwIUAeoxOcMWhLCoyQWbmoq1tH63OBm-C9ilyy2xQMRrvQqZck636MNioukw1axuC7dP9p42rLAkG61Xs_dcPOHrrVDpHr3TMrGuNjhv6DB21qgvmfLdP0dvD_ev8KV-8PD7PZ4tcUyFiTrlmvKCkbioumGGsVobURSNoy6pSASccK11oQozBkKAG86rkRasbKmqj6BTdbPMOvv8YTYgy9atN1yln-jFILjhJQ4AEXv0B3_vRu9SbJJixioqySBDeQtr3IXjTysHbdfqfxCA3BsitATIZIDcGSJ40l7vEY702zV6xm3gCrneAClp1rVdO2_DLESgZ4WxTnGy5kJ7c0vh9h_9X_wb7mp73</recordid><startdate>20081001</startdate><enddate>20081001</enddate><creator>Fernández Urrusuno, Rocío</creator><creator>Pedregal González, Miguel</creator><creator>Torrecilla Rojas, Ma. Amparo</creator><general>Springer-Verlag</general><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7TK</scope><scope>7U9</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>CCPQU</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>7X8</scope></search><sort><creationdate>20081001</creationdate><title>Antibiotic prescribing patterns and hospital admissions with respiratory and urinary tract infections</title><author>Fernández Urrusuno, Rocío ; Pedregal González, Miguel ; Torrecilla Rojas, Ma. Amparo</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c399t-36c46532bd8694e44bae2b5d93f487a06261ac5c22ee10d86d168765fcd39bea3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Anti-Bacterial Agents - therapeutic use</topic><topic>Antibiotics</topic><topic>Bacterial diseases</topic><topic>Bacterial diseases of the urinary system</topic><topic>Biological and medical sciences</topic><topic>Biomedical and Life Sciences</topic><topic>Biomedicine</topic><topic>Cross-Sectional Studies</topic><topic>Drug Utilization</topic><topic>Female</topic><topic>Hospitalization - statistics & numerical data</topic><topic>Human bacterial diseases</topic><topic>Humans</topic><topic>Infections</topic><topic>Infectious diseases</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Nephrology. Urinary tract diseases</topic><topic>Outcome Assessment (Health Care)</topic><topic>Pharmacoepidemiology and Prescription</topic><topic>Pharmacology. Drug treatments</topic><topic>Pharmacology/Toxicology</topic><topic>Physicians, Family - statistics & numerical data</topic><topic>Prescriptions</topic><topic>Primary care</topic><topic>Respiratory diseases</topic><topic>Respiratory Tract Infections - complications</topic><topic>Respiratory Tract Infections - drug therapy</topic><topic>Retrospective Studies</topic><topic>Urinary system involvement in other diseases. Miscellaneous</topic><topic>Urinary tract diseases</topic><topic>Urinary Tract Infections - complications</topic><topic>Urinary Tract Infections - drug therapy</topic><topic>Urinary tract. Prostate gland</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Fernández Urrusuno, Rocío</creatorcontrib><creatorcontrib>Pedregal González, Miguel</creatorcontrib><creatorcontrib>Torrecilla Rojas, Ma. 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Amparo</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Antibiotic prescribing patterns and hospital admissions with respiratory and urinary tract infections</atitle><jtitle>European journal of clinical pharmacology</jtitle><stitle>Eur J Clin Pharmacol</stitle><addtitle>Eur J Clin Pharmacol</addtitle><date>2008-10-01</date><risdate>2008</risdate><volume>64</volume><issue>10</issue><spage>1005</spage><epage>1011</epage><pages>1005-1011</pages><issn>0031-6970</issn><eissn>1432-1041</eissn><abstract>Objective
To explore the relationship between antibiotic prescribing indicators for assessing the prescribing quality of general practitioners (GPs) and populations’ health outcome indicators.
Design
Descriptive cross-sectional study.
Setting
Aljarafe Primary Health Care Area (population 321,034) under the administrative jurisdiction of the Andalusian Public Health Care Service, Spain. In total, 162 GPs, representing 95.29% of the total number of GPs in the study area, were included in the analysis.
Methods
Antibiotic prescribing indicators based on clinical evidence and recommendations from local resistance patterns were chosen by the consensus group technique. Hospital admissions due to respiratory tract and urinary infections in the three hospitals of the study area were recorded. Multiple regression analysis was carried out to determine the relationship between community prescribing of antibiotics and hospital admissions due to serious complications from respiratory and urinary infections.
Results
The higher prescribing of antibiotics adjusted for patients and working days was associated with a significantly higher number of adjusted hospital admissions due complications arising from respiratory and urinary infections (
p
< 0.001) (
R
2
= 0.142). This relationship was not found for indicators based on the relative prescribing of recommended first-line versus second and third-line antibiotics. There were fewer patients of women GPs admitted to hospitals (
p
= 0.021).
Conclusions
Our findings show a statistically significant relationship—at the GPs level—between the quantitative antibiotic prescribing rate and standardized hospital admissions due to complications arising from respiratory and urinary infections of the assisted patients. Strategies should be addressed to reduce unnecessary antibiotic prescribing in primary care.</abstract><cop>Berlin/Heidelberg</cop><pub>Springer-Verlag</pub><pmid>18607582</pmid><doi>10.1007/s00228-008-0514-6</doi><tpages>7</tpages></addata></record> |
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| ispartof | European journal of clinical pharmacology, 2008-10, Vol.64 (10), p.1005-1011 |
| issn | 0031-6970 1432-1041 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69620150 |
| source | Springer Nature |
| subjects | Anti-Bacterial Agents - therapeutic use Antibiotics Bacterial diseases Bacterial diseases of the urinary system Biological and medical sciences Biomedical and Life Sciences Biomedicine Cross-Sectional Studies Drug Utilization Female Hospitalization - statistics & numerical data Human bacterial diseases Humans Infections Infectious diseases Male Medical sciences Middle Aged Nephrology. Urinary tract diseases Outcome Assessment (Health Care) Pharmacoepidemiology and Prescription Pharmacology. Drug treatments Pharmacology/Toxicology Physicians, Family - statistics & numerical data Prescriptions Primary care Respiratory diseases Respiratory Tract Infections - complications Respiratory Tract Infections - drug therapy Retrospective Studies Urinary system involvement in other diseases. Miscellaneous Urinary tract diseases Urinary Tract Infections - complications Urinary Tract Infections - drug therapy Urinary tract. Prostate gland |
| title | Antibiotic prescribing patterns and hospital admissions with respiratory and urinary tract infections |
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