Platelet-Rich Plasma for Pediatric Tonsillectomy Patients

Objectives/Hypothesis: To determine if placement of autologous platelet‐rich plasma (PRP) on the tonsil beds at the time of tonsillectomy would decrease postoperative pain and complications. Study Design: Double blind, randomized, prospective study. Methods: Seventy children were recruited to partic...

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Bibliographic Details
Published in:The Laryngoscope 2008-10, Vol.118 (10), p.1765-1767
Main Authors: Sidman, James D., Lander, Timothy A., Finkelstein, Marsha
Format: Article
Language:English
Subjects:
Adolescent
Biological and medical sciences
Child
Child, Preschool
Double-Blind Method
Female
Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics
Humans
Male
Medical sciences
Otorhinolaryngology. Stomatology
Pain, Postoperative - prevention & control
Platelet-Rich Plasma
postoperative pain
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the upper aerodigestive tract
Tonsillectomy
Tonsils
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Summary:Objectives/Hypothesis: To determine if placement of autologous platelet‐rich plasma (PRP) on the tonsil beds at the time of tonsillectomy would decrease postoperative pain and complications. Study Design: Double blind, randomized, prospective study. Methods: Seventy children were recruited to participate in the study, ranging in age from 4 to 15 years. They were randomized to treatment (PRP) or control groups. The parents, patients, and nurses were blinded as to which group they were in. Postoperative pain scores were obtained using the FACES pain scale and recorded in a home diary. Results: Seventy patients were recruited to the study, and 12 did not submit their diaries and were considered to drop out of the study. Demographic data were similar for both control and treatment groups. Median pain scores, medication use, days to normal diet, and office visits did not differ between the two groups. Conclusions: PRP applied once at the time of tonsillectomy does not improve postoperative pain or recovery in pediatric patients.
ISSN:0023-852X
1531-4995
DOI:10.1097/MLG.0b013e31817f18e7