A new taxonomy of mammalian MHC class I molecules

With the continuing identification of new and divergent major histocompatibility complex (MHC) class I proteins, some with potentially novel functions, the 'class Ib' category is now outdated. Here, Austin Hughes and colleagues propose a change in the way we classify class I genes and thei...

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Bibliographic Details
Published in:Immunology today (Amsterdam. Regular ed.) 1999-01, Vol.20 (1), p.22-26
Main Authors: Hughes, A L, Yeager, M, Ten Elshof, A E, Chorney, M J
Format: Article
Language:English
Subjects:
Animals
Antigens, CD1 - classification
Antigens, CD1 - genetics
Birds - genetics
Birds - immunology
Evolution, Molecular
H-2 Antigens - classification
H-2 Antigens - genetics
Hemochromatosis Protein
Histocompatibility Antigens Class I - classification
Histocompatibility Antigens Class I - genetics
HLA Antigens - classification
HLA Antigens - genetics
Humans
Mammalia
Mammals - genetics
Mammals - immunology
Membrane Proteins
Mice
Phylogeny
Terminology as Topic
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Summary:With the continuing identification of new and divergent major histocompatibility complex (MHC) class I proteins, some with potentially novel functions, the 'class Ib' category is now outdated. Here, Austin Hughes and colleagues propose a change in the way we classify class I genes and their products.
ISSN:0167-5699
DOI:10.1016/S0167-5699(98)01377-2