Analysis of Leucocyte Subsets in the Canine Intestine

Immunohistochemistry and computer-aided morphometric analysis were used to define populations of leucocyte subsets in the intestinal tract of an outbred population of dogs with no evidence of gastrointestinal disease. In the small intestinal lamina propria, B cells and plasma cells (IgA+, IgM+and Ig...

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Bibliographic Details
Published in:Journal of comparative pathology 1999-02, Vol.120 (2), p.129-145
Main Authors: German, A.J., Hall, E.J., Day, M.J.
Format: Article
Language:English
Subjects:
Age Factors
Animals
Automatic Data Processing
B-Lymphocytes - cytology
B-Lymphocytes - immunology
Dogs
Eosinophils - cytology
Eosinophils - immunology
Female
Immunity, Cellular
Immunohistochemistry
Intestines - anatomy & histology
Intestines - immunology
Leukocyte Count - methods
Leukocytes - classification
Leukocytes - cytology
Male
Mast Cells - cytology
Mast Cells - immunology
T-Lymphocytes - cytology
T-Lymphocytes - immunology
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Summary:Immunohistochemistry and computer-aided morphometric analysis were used to define populations of leucocyte subsets in the intestinal tract of an outbred population of dogs with no evidence of gastrointestinal disease. In the small intestinal lamina propria, B cells and plasma cells (IgA+, IgM+and IgG+) were prominent in peri-crypt regions, with a significant trend for a reduction in the number of cells towards the villous tip (P
ISSN:0021-9975
1532-3129
DOI:10.1053/jcpa.1998.0262