Algorithm for the prevention of ventricular tachycardia onset: the prevent study

The Prevent Study is designed to investigate the effect of a rate-smoothing algorithm on the onset of ventricular tachycardia in patients with implanted cardioverter defibrillators (ICD) with dual-chamber pacing and sensing function. Included in the study are patients who require ICD therapy for rec...

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Bibliographic Details
Published in:The American journal of cardiology 1999-03, Vol.83 (5), p.45-47
Main Authors: Fromer, Martin, Wietholt, Dietmer
Format: Article
Language:English
Subjects:
Algorithms
Biological and medical sciences
Cardiac arrhythmia
Cardiac dysrhythmias
Cardiology
Cardiology. Vascular system
Electrocardiography
Equipment Design
Heart
Heart Arrest - etiology
Heart Arrest - prevention & control
Heart Arrest - therapy
Heart Rate
Humans
Medical research
Medical sciences
Pacemaker, Artificial
Preventive medicine
Quality of Life
Recurrence
Tachycardia, Ventricular - etiology
Tachycardia, Ventricular - prevention & control
Tachycardia, Ventricular - therapy
Transplants & implants
Treatment Outcome
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Summary:The Prevent Study is designed to investigate the effect of a rate-smoothing algorithm on the onset of ventricular tachycardia in patients with implanted cardioverter defibrillators (ICD) with dual-chamber pacing and sensing function. Included in the study are patients who require ICD therapy for recurrent ventricular tachycardia or aborted cardiac arrest. After giving informed consent to the study, the patients receive a Ventak AV ICD (CPI-Guidant, St. Paul, MN). The patients are randomized to start either with active or inactive rate-smoothing algorithm. After 3 months, all patients cross over to the opposite group. Questionnaires are used to investigate quality-of-life issues. A total of 240 patients will be enrolled in the study, with a minimum follow-up of 6 months.
ISSN:0002-9149
1879-1913
DOI:10.1016/S0002-9149(98)00968-0