Traumatic extra-axial hemorrhage: Correlation of postmortem MSCT, MRI, and forensic-pathological findings

• Published in: Journal of magnetic resonance imaging 2008-10, Vol.28 (4), p.823-836
• Main Authors: Añon, Javier, Remonda, Luca, Spreng, Adrian, Scheurer, Eva, Schroth, Gerhard, Boesch, Chris, Thali, Michael, Dirnhofer, Richard, Yen, Kathrin
• Format: Article
• Language: English
• Subjects: Adolescent; Adult; Aged; Aged, 80 and over; Autopsy; Child; Child, Preschool; correlation; Craniocerebral Trauma - pathology; Female; forensic neuropathology; Hemorrhage - pathology; Humans; Infant; Magnetic Resonance Imaging - methods; Male; Middle Aged; postmortem MRI; postmortem MSCT; Predictive Value of Tests; Retrospective Studies; Sensitivity and Specificity; Tomography, X-Ray Computed - methods; traumatic extra-axial hemorrhage
• ISSN: 1053-1807; 1522-2586
• DOI: 10.1002/jmri.21495

Purpose To evaluate the diagnostic accuracy of in situ postmortem multislice computed tomography (MSCT) and magnetic resonance imaging (MRI) in the detection of primary traumatic extra‐axial hemorrhage. Materials and Methods Thirty forensic neurotrauma cases and 10 nontraumatic controls who underwent both in situ postmortem cranial MSCT and MR imaging before autopsy were retrospectively reviewed. Both imaging modalities were analyzed in view of their accuracy, sensitivity, and specificity concerning the detection of extra‐axial hemorrhage. Statistical significance was calculated using the McNemar test. κ values for interobserver agreement were calculated for extra‐axial hemorrhage types and to quantify the agreement between both modalities as well as MRI, CT, and forensics, respectively. Results Analysis of the detection of hemorrhagic localizations showed an accuracy, sensitivity, and specificity of 89%, 82%, and 92% using CT, and 90%, 83%, and 94% using MRI, respectively. MRI was more sensitive than CT in the detection of subarachnoid hemorrhagic localizations (P = 0.001), whereas no significant difference resulted from the detection of epidural and subdural hemorrhagic findings (P = 0.248 and P = 0.104, respectively). Interobserver agreement for all extra‐axial hemorrhage types was substantial (CT κ = 0.76; MRI κ = 0.77). The agreement of both modalitites was almost perfect (readers 1 and 2 κ = 0.88). Conclusion CT and MRI are of comparable potential as forensic diagnostic tools for traumatic extra‐axial hemorrhage. Not only of forensic, but also of clinical interest is the observation that most thin blood layers escape the radiological evaluation. J. Magn. Reson. Imaging 2008;28:823–836. © 2008 Wiley‐Liss, Inc.