Cardiovascular morbidity and risk factors in renal transplant patients

BACKGROUND: Cardiovascular disease is now the major cause of death in renal transplant patients. This study aimed to assess the prevalence of cardiovascular disease in stable renal transplant patients as compared with the general background population, and to assess risk factors for cardiovascular d...

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Bibliographic Details
Published in:Nephrology, dialysis, transplantation dialysis, transplantation, 1999-03, Vol.14 (3), p.648-654
Main Authors: Aakhus, S, Dahl, K, Widerøe, T E
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Biological and medical sciences
Cardiovascular Diseases - etiology
Cross-Sectional Studies
Female
Humans
Hypertension - etiology
Hypertrophy, Left Ventricular - etiology
Kidney Transplantation - adverse effects
Male
Medical sciences
Middle Aged
Myocardial Ischemia - etiology
Risk Factors
Sex Factors
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the urinary system
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Summary:BACKGROUND: Cardiovascular disease is now the major cause of death in renal transplant patients. This study aimed to assess the prevalence of cardiovascular disease in stable renal transplant patients as compared with the general background population, and to assess risk factors for cardiovascular disease in this patient group. METHODS: A cross-sectional multicentre study comprising 406 stable renal transplant patients (age 47+/-16 years, 60% males, 71% taking cyclosporin A) were assessed clinically and biochemically 48 months (median) after transplantation and compared with the general population. Multivariate analysis was used to assess the relation between cardiovascular disease and risk factors. RESULTS: Hypertension was present in 55% of males and 34% of females (P
ISSN:0931-0509
1460-2385
DOI:10.1093/ndt/14.3.648