Atopic features in early childhood autism

Abstract Background Autism is a developmental disorder of unknown etiology. Sensitivity to dietary and environmental antigens has been considered in its pathogenesis. Aim To examine immediate hypersensitivity in early childhood autism. Methods We investigated 30 autistic children (23 boys, seven gir...

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Bibliographic Details
Published in:European journal of paediatric neurology 2008-11, Vol.12 (6), p.476-479
Main Authors: Bakkaloglu, Betul, Anlar, Banu, Anlar, F. Yasar, Öktem, Ferhunde, Pehlivantürk, Berna, Ünal, Fatih, Ozbesler, Cengiz, Gökler, Bahar
Format: Article
Language:English
Subjects:
Allergy
Antigen
Autism
Autistic Disorder - complications
Child, Preschool
Diet
Female
Humans
Hypersensitivity, Immediate - complications
Hypersensitivity, Immediate - diagnosis
Hypersensitivity, Immediate - epidemiology
Immunoglobulin A - blood
Immunoglobulin G - blood
Immunoglobulin M - blood
Male
Neurology
Pediatrics
Pervasive developmental disorder
Psychiatric Status Rating Scales
Skin Tests
Surveys and Questionnaires
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Summary:Abstract Background Autism is a developmental disorder of unknown etiology. Sensitivity to dietary and environmental antigens has been considered in its pathogenesis. Aim To examine immediate hypersensitivity in early childhood autism. Methods We investigated 30 autistic children (23 boys, seven girls 2–4 years old) for atopic history, serum IgG, IgA, IgM, IgE levels, and skin prick tests (SPT) with 12 common antigens. Results Nine/30 autistic children (30%) and 1/39 (2.5%) age-matched neurological controls from the same hospital had a family history suggestive of atopy ( p
ISSN:1090-3798
1532-2130
DOI:10.1016/j.ejpn.2007.12.008