Mortality Incidence and the Severity of Coronary Atherosclerosis Assessed by Computed Tomography Angiography

Objectives This study investigated whether cardiac computed tomography angiography (CTA) can predict all-cause mortality in symptomatic patients. Background Noninvasive coronary angiography is being increasingly performed by CTA to assess for obstructive coronary artery disease (CAD), and minimal ou...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the American College of Cardiology 2008-10, Vol.52 (16), p.1335-1343
Main Authors: Ostrom, Matthew P., MD, Gopal, Ambarish, MD, Ahmadi, Naser, MD, Nasir, Khurram, MD, MPH, Yang, Eric, MD, Kakadiaris, Ioannis, PhD, Flores, Ferdinand, BS, Mao, Song S., MD, Budoff, Matthew J., MD
Format: Article
Language:English
Subjects:
Adult
Age Factors
Aged
Aged, 80 and over
cardiac CT
Cardiology
Cardiovascular
Cardiovascular disease
Cause of Death
Cohort Studies
Confidence Intervals
Contrast Media - pharmacology
Coronary Angiography - methods
Coronary Artery Disease - diagnostic imaging
Coronary Artery Disease - mortality
Coronary Artery Disease - physiopathology
coronary calcium
Coronary vessels
CT angiography
Female
Heart attacks
Humans
Incidence
Internal Medicine
Kaplan-Meier Estimate
Male
Medical imaging
Middle Aged
Mortality
outcomes
Predictive Value of Tests
Prognosis
Proportional Hazards Models
Radiographic Image Enhancement
Risk Assessment
ROC Curve
Sensitivity and Specificity
Severity of Illness Index
Sex Factors
Survival Analysis
Tomography, X-Ray Computed - methods
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Objectives This study investigated whether cardiac computed tomography angiography (CTA) can predict all-cause mortality in symptomatic patients. Background Noninvasive coronary angiography is being increasingly performed by CTA to assess for obstructive coronary artery disease (CAD), and minimal outcome data exist for coronary CTA. We have utilized a cohort of symptomatic patients who underwent electron beam tomography to allow for longer follow-up (up to 12 years) than currently available with newer 64-slice multidetector-row computed tomography studies. Methods In all, 2,538 consecutive patients who underwent CTA by electron beam tomography (age 59 ± 14 years, 70% males) without known CAD were studied. Computed tomographic angiography results were categorized as significant CAD (≥50% luminal narrowing), mild CAD (
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2008.07.027