Plasma chain-breaking antioxidants in Alzheimer's disease, vascular dementia and Parkinson's disease

We studied the plasma chain-breaking antioxidants α carotene, β carotene, lycopene, Vitamin A, Vitamin C, Vitamin E and a measure of total antioxidant capacity, TAC, in 79 patients with Alzheimer's disease (AD), 37 patients with vascular dementia (VaD), 18 patients with Parkinson's disease...

Full description

Saved in:
Bibliographic Details
Published in:QJM : An International Journal of Medicine 1999-01, Vol.92 (1), p.39-45
Main Authors: Foy, C.J., Passmore, A.P., Vahidassr, M.D., Young, I.S., Lawson, J.T.
Format: Article
Language:English
Subjects:
Aged
Aged, 80 and over
Alzheimer Disease - metabolism
Antioxidants - metabolism
Biological and medical sciences
Carotenoids - metabolism
Degenerative and inherited degenerative diseases of the nervous system. Leukodystrophies. Prion diseases
Dementia, Vascular - metabolism
Female
Free Radicals - metabolism
Humans
Male
Medical sciences
Middle Aged
Neurology
Oxidation-Reduction
Parkinson Disease - metabolism
Vitamins - metabolism
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We studied the plasma chain-breaking antioxidants α carotene, β carotene, lycopene, Vitamin A, Vitamin C, Vitamin E and a measure of total antioxidant capacity, TAC, in 79 patients with Alzheimer's disease (AD), 37 patients with vascular dementia (VaD), 18 patients with Parkinson's disease and dementia (PDem), and 58 matching controls, together with 41 patients with Parkinson's disease (PD) and 41 matching controls. Significant reductions in individual antioxidants were observed in all dementia groups. When compared to controls, the following were reduced: Vitamin A in AD (p
ISSN:1460-2725
1460-2393
1460-2393
DOI:10.1093/qjmed/92.1.39