Early temporal expression of soluble cellular adhesion molecules in patients with unstable angina and subendocardial myocardial infarction

Inflammation is increasingly considered to be involved in the pathogenesis of acute coronary syndromes. We documented persistent elevation in the levels of soluble ICAM-1 and soluble VCAM-1 and a decrease in the levels of soluble E-selectin in the first 72 hours of acute presentation in patients wit...

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Bibliographic Details
Published in:The American journal of cardiology 1999-04, Vol.83 (8), p.1265-1267
Main Authors: Mulvihill, Niall, Foley, J.Brendan, Ghaisas, Nitin, Murphy, Ross, Crean, Peter, Walsh, Michael
Format: Article
Language:English
Subjects:
Angina pectoris
Angina, Unstable - blood
Biological and medical sciences
Biomarkers - blood
Cardiology
Cardiology. Vascular system
Cardiovascular disease
Coronary heart disease
E-Selectin - blood
Electrocardiography
Female
Follow-Up Studies
Heart
Heart attacks
Humans
Intercellular Adhesion Molecule-1 - biosynthesis
Male
Medical sciences
Middle Aged
Molecular biology
Myocardial Infarction - blood
Prognosis
Severity of Illness Index
Vascular Cell Adhesion Molecule-1 - biosynthesis
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Summary:Inflammation is increasingly considered to be involved in the pathogenesis of acute coronary syndromes. We documented persistent elevation in the levels of soluble ICAM-1 and soluble VCAM-1 and a decrease in the levels of soluble E-selectin in the first 72 hours of acute presentation in patients with unstable angina and subendocardial myocardial infarction.
ISSN:0002-9149
1879-1913
DOI:10.1016/S0002-9149(99)00070-3