Loading…
Lipoprotein (a) level in the population in Taiwan: relationship to sociodemographic and atherosclerotic risk factors
To examine the lipoprotein(a) (Lp(a)) level in the Taiwanese population and its association with cardiovascular risk factors, 1703 men and 1899 women aged 35 years and above were enrolled in a community-based study cohort established between 1990 and 1991. The distributions of Lp(a) levels were skew...
Saved in:
| Published in: | Atherosclerosis 1999-04, Vol.143 (2), p.267-273 |
|---|---|
| Main Authors: | , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Citations: | Items that this one cites Items that cite this one |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | cdi_FETCH-LOGICAL-c503t-a51533a2303db38a5d69b2fac924eb08f130170d4ee78bd63d4dab87366cc2113 |
|---|---|
| cites | cdi_FETCH-LOGICAL-c503t-a51533a2303db38a5d69b2fac924eb08f130170d4ee78bd63d4dab87366cc2113 |
| container_end_page | 273 |
| container_issue | 2 |
| container_start_page | 267 |
| container_title | Atherosclerosis |
| container_volume | 143 |
| creator | Chien, Kuo-Liong Lee, Yuan-Teh Sung, Fung-Chang Su, Ta-Chen Hsu, Hsiu-Ching Lin, Ruey-Shiung |
| description | To examine the lipoprotein(a) (Lp(a)) level in the Taiwanese population and its association with cardiovascular risk factors, 1703 men and 1899 women aged 35 years and above were enrolled in a community-based study cohort established between 1990 and 1991. The distributions of Lp(a) levels were skewed to the right, and females were more likely than males to have Lp(a) levels greater than 30 mg/dl (14.3% versus 11.6%,
P |
| doi_str_mv | 10.1016/S0021-9150(98)00298-6 |
| format | article |
| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69714795</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><els_id>S0021915098002986</els_id><sourcerecordid>69714795</sourcerecordid><originalsourceid>FETCH-LOGICAL-c503t-a51533a2303db38a5d69b2fac924eb08f130170d4ee78bd63d4dab87366cc2113</originalsourceid><addsrcrecordid>eNqFkE-PFCEQxYnRuOPqR9BwMGb30ApN08BejNn4L5nEg-uZVEO1g_Y0LTBr_PYy2xP15gVSr371KB4hTzl7yRnvX31mrOWN4ZJdGH1ZC6Ob_h7ZcK1Mwzvd3SebP8gZeZTzN8ZYp7h-SM54bSgh5YaUbVjikmLBMNMLuKQT3uJEa1F2SGvrMEEJcT4qNxB-wnxFE65a3oWFlkhzdCF63MevCZZdcBRmT6HOp5jdVM9StRTydzqCKzHlx-TBCFPGJ6f7nHx59_bm-kOz_fT-4_WbbeMkE6UByaUQ0Aom_CA0SN-boa0epu1wYHrkgnHFfIeo9OB74TsPg1ai751rORfn5MXqWz_444C52H3IDqcJZoyHbHujeKeMrKBcQVdXzglHu6Swh_TLcmaPcdu7uO0xS2u0vYvb9nXu2emBw7BH_8_Umm8Fnp8AyA6mMcHsQv7LqerDdMVerxjWNG4DJptdwNmhDwldsT6G_2zyGwyqnaY</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>69714795</pqid></control><display><type>article</type><title>Lipoprotein (a) level in the population in Taiwan: relationship to sociodemographic and atherosclerotic risk factors</title><source>ScienceDirect Freedom Collection 2022-2024</source><creator>Chien, Kuo-Liong ; Lee, Yuan-Teh ; Sung, Fung-Chang ; Su, Ta-Chen ; Hsu, Hsiu-Ching ; Lin, Ruey-Shiung</creator><creatorcontrib>Chien, Kuo-Liong ; Lee, Yuan-Teh ; Sung, Fung-Chang ; Su, Ta-Chen ; Hsu, Hsiu-Ching ; Lin, Ruey-Shiung</creatorcontrib><description>To examine the lipoprotein(a) (Lp(a)) level in the Taiwanese population and its association with cardiovascular risk factors, 1703 men and 1899 women aged 35 years and above were enrolled in a community-based study cohort established between 1990 and 1991. The distributions of Lp(a) levels were skewed to the right, and females were more likely than males to have Lp(a) levels greater than 30 mg/dl (14.3% versus 11.6%,
P<0.05). The Lp(a) level increased with age. Socioeconomic status did not seem to have consistent influence on the level of Lp(a). Smoking and alcohol use also had no effect on Lp(a) levels. Multivariate analysis indicated that older age and high level of low-density-lipoprotein cholesterol corresponded to an elevated Lp(a) level, while hypertriglyceridemia, low high-density-lipoprotein cholesterol level, obesity and high insulin resistance corresponded to a lower Lp(a) level. In univariate analysis, hyperinsulinemia was negatively associated with Lp(a) level (−0.107,
P<0.01) only in males. In females, use of oral contraceptive lowered Lp(a) levels, but menopause did not change Lp(a) levels. We also found that different correlation patterns existed for selected coagulation profiles between sexes. There was a significant correlation between Lp(a) and fibrinogen levels in males (0.154,
P<0.001) but not in females (0.007,
P>0.05). These data provided clues for investigating atherosclerotic risk factors and coagulation parameters for the Taiwanese population.</description><identifier>ISSN: 0021-9150</identifier><identifier>EISSN: 1879-1484</identifier><identifier>DOI: 10.1016/S0021-9150(98)00298-6</identifier><identifier>PMID: 10217355</identifier><language>eng</language><publisher>Amsterdam: Elsevier Ireland Ltd</publisher><subject>Adult ; Age Distribution ; Aged ; Analysis of Variance ; Arteriosclerosis - blood ; Arteriosclerosis - epidemiology ; Arteriosclerosis - etiology ; Atherosclerosis ; Atherosclerosis (general aspects, experimental research) ; Biological and medical sciences ; Blood and lymphatic vessels ; Cardiology. Vascular system ; Cardiovascular Diseases - blood ; Cardiovascular Diseases - epidemiology ; Cardiovascular Diseases - etiology ; Cohort Studies ; Female ; Health Surveys ; Humans ; Incidence ; Lipoprotein(a) ; Lipoprotein(a) - adverse effects ; Lipoprotein(a) - blood ; Lipoproteins - blood ; Male ; Medical sciences ; Middle Aged ; Multivariate Analysis ; Obesity - blood ; Obesity - epidemiology ; Population-based ; Risk Factors ; Sex Characteristics ; Socioeconomic Factors ; Taiwan - epidemiology ; Taiwanese</subject><ispartof>Atherosclerosis, 1999-04, Vol.143 (2), p.267-273</ispartof><rights>1999 Elsevier Science Ireland Ltd</rights><rights>1999 INIST-CNRS</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c503t-a51533a2303db38a5d69b2fac924eb08f130170d4ee78bd63d4dab87366cc2113</citedby><cites>FETCH-LOGICAL-c503t-a51533a2303db38a5d69b2fac924eb08f130170d4ee78bd63d4dab87366cc2113</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,777,781,27905,27906</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1729808$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10217355$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Chien, Kuo-Liong</creatorcontrib><creatorcontrib>Lee, Yuan-Teh</creatorcontrib><creatorcontrib>Sung, Fung-Chang</creatorcontrib><creatorcontrib>Su, Ta-Chen</creatorcontrib><creatorcontrib>Hsu, Hsiu-Ching</creatorcontrib><creatorcontrib>Lin, Ruey-Shiung</creatorcontrib><title>Lipoprotein (a) level in the population in Taiwan: relationship to sociodemographic and atherosclerotic risk factors</title><title>Atherosclerosis</title><addtitle>Atherosclerosis</addtitle><description>To examine the lipoprotein(a) (Lp(a)) level in the Taiwanese population and its association with cardiovascular risk factors, 1703 men and 1899 women aged 35 years and above were enrolled in a community-based study cohort established between 1990 and 1991. The distributions of Lp(a) levels were skewed to the right, and females were more likely than males to have Lp(a) levels greater than 30 mg/dl (14.3% versus 11.6%,
P<0.05). The Lp(a) level increased with age. Socioeconomic status did not seem to have consistent influence on the level of Lp(a). Smoking and alcohol use also had no effect on Lp(a) levels. Multivariate analysis indicated that older age and high level of low-density-lipoprotein cholesterol corresponded to an elevated Lp(a) level, while hypertriglyceridemia, low high-density-lipoprotein cholesterol level, obesity and high insulin resistance corresponded to a lower Lp(a) level. In univariate analysis, hyperinsulinemia was negatively associated with Lp(a) level (−0.107,
P<0.01) only in males. In females, use of oral contraceptive lowered Lp(a) levels, but menopause did not change Lp(a) levels. We also found that different correlation patterns existed for selected coagulation profiles between sexes. There was a significant correlation between Lp(a) and fibrinogen levels in males (0.154,
P<0.001) but not in females (0.007,
P>0.05). These data provided clues for investigating atherosclerotic risk factors and coagulation parameters for the Taiwanese population.</description><subject>Adult</subject><subject>Age Distribution</subject><subject>Aged</subject><subject>Analysis of Variance</subject><subject>Arteriosclerosis - blood</subject><subject>Arteriosclerosis - epidemiology</subject><subject>Arteriosclerosis - etiology</subject><subject>Atherosclerosis</subject><subject>Atherosclerosis (general aspects, experimental research)</subject><subject>Biological and medical sciences</subject><subject>Blood and lymphatic vessels</subject><subject>Cardiology. Vascular system</subject><subject>Cardiovascular Diseases - blood</subject><subject>Cardiovascular Diseases - epidemiology</subject><subject>Cardiovascular Diseases - etiology</subject><subject>Cohort Studies</subject><subject>Female</subject><subject>Health Surveys</subject><subject>Humans</subject><subject>Incidence</subject><subject>Lipoprotein(a)</subject><subject>Lipoprotein(a) - adverse effects</subject><subject>Lipoprotein(a) - blood</subject><subject>Lipoproteins - blood</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Middle Aged</subject><subject>Multivariate Analysis</subject><subject>Obesity - blood</subject><subject>Obesity - epidemiology</subject><subject>Population-based</subject><subject>Risk Factors</subject><subject>Sex Characteristics</subject><subject>Socioeconomic Factors</subject><subject>Taiwan - epidemiology</subject><subject>Taiwanese</subject><issn>0021-9150</issn><issn>1879-1484</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><recordid>eNqFkE-PFCEQxYnRuOPqR9BwMGb30ApN08BejNn4L5nEg-uZVEO1g_Y0LTBr_PYy2xP15gVSr371KB4hTzl7yRnvX31mrOWN4ZJdGH1ZC6Ob_h7ZcK1Mwzvd3SebP8gZeZTzN8ZYp7h-SM54bSgh5YaUbVjikmLBMNMLuKQT3uJEa1F2SGvrMEEJcT4qNxB-wnxFE65a3oWFlkhzdCF63MevCZZdcBRmT6HOp5jdVM9StRTydzqCKzHlx-TBCFPGJ6f7nHx59_bm-kOz_fT-4_WbbeMkE6UByaUQ0Aom_CA0SN-boa0epu1wYHrkgnHFfIeo9OB74TsPg1ai751rORfn5MXqWz_444C52H3IDqcJZoyHbHujeKeMrKBcQVdXzglHu6Swh_TLcmaPcdu7uO0xS2u0vYvb9nXu2emBw7BH_8_Umm8Fnp8AyA6mMcHsQv7LqerDdMVerxjWNG4DJptdwNmhDwldsT6G_2zyGwyqnaY</recordid><startdate>19990401</startdate><enddate>19990401</enddate><creator>Chien, Kuo-Liong</creator><creator>Lee, Yuan-Teh</creator><creator>Sung, Fung-Chang</creator><creator>Su, Ta-Chen</creator><creator>Hsu, Hsiu-Ching</creator><creator>Lin, Ruey-Shiung</creator><general>Elsevier Ireland Ltd</general><general>Elsevier</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>19990401</creationdate><title>Lipoprotein (a) level in the population in Taiwan: relationship to sociodemographic and atherosclerotic risk factors</title><author>Chien, Kuo-Liong ; Lee, Yuan-Teh ; Sung, Fung-Chang ; Su, Ta-Chen ; Hsu, Hsiu-Ching ; Lin, Ruey-Shiung</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c503t-a51533a2303db38a5d69b2fac924eb08f130170d4ee78bd63d4dab87366cc2113</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Adult</topic><topic>Age Distribution</topic><topic>Aged</topic><topic>Analysis of Variance</topic><topic>Arteriosclerosis - blood</topic><topic>Arteriosclerosis - epidemiology</topic><topic>Arteriosclerosis - etiology</topic><topic>Atherosclerosis</topic><topic>Atherosclerosis (general aspects, experimental research)</topic><topic>Biological and medical sciences</topic><topic>Blood and lymphatic vessels</topic><topic>Cardiology. Vascular system</topic><topic>Cardiovascular Diseases - blood</topic><topic>Cardiovascular Diseases - epidemiology</topic><topic>Cardiovascular Diseases - etiology</topic><topic>Cohort Studies</topic><topic>Female</topic><topic>Health Surveys</topic><topic>Humans</topic><topic>Incidence</topic><topic>Lipoprotein(a)</topic><topic>Lipoprotein(a) - adverse effects</topic><topic>Lipoprotein(a) - blood</topic><topic>Lipoproteins - blood</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Middle Aged</topic><topic>Multivariate Analysis</topic><topic>Obesity - blood</topic><topic>Obesity - epidemiology</topic><topic>Population-based</topic><topic>Risk Factors</topic><topic>Sex Characteristics</topic><topic>Socioeconomic Factors</topic><topic>Taiwan - epidemiology</topic><topic>Taiwanese</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Chien, Kuo-Liong</creatorcontrib><creatorcontrib>Lee, Yuan-Teh</creatorcontrib><creatorcontrib>Sung, Fung-Chang</creatorcontrib><creatorcontrib>Su, Ta-Chen</creatorcontrib><creatorcontrib>Hsu, Hsiu-Ching</creatorcontrib><creatorcontrib>Lin, Ruey-Shiung</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Atherosclerosis</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Chien, Kuo-Liong</au><au>Lee, Yuan-Teh</au><au>Sung, Fung-Chang</au><au>Su, Ta-Chen</au><au>Hsu, Hsiu-Ching</au><au>Lin, Ruey-Shiung</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Lipoprotein (a) level in the population in Taiwan: relationship to sociodemographic and atherosclerotic risk factors</atitle><jtitle>Atherosclerosis</jtitle><addtitle>Atherosclerosis</addtitle><date>1999-04-01</date><risdate>1999</risdate><volume>143</volume><issue>2</issue><spage>267</spage><epage>273</epage><pages>267-273</pages><issn>0021-9150</issn><eissn>1879-1484</eissn><abstract>To examine the lipoprotein(a) (Lp(a)) level in the Taiwanese population and its association with cardiovascular risk factors, 1703 men and 1899 women aged 35 years and above were enrolled in a community-based study cohort established between 1990 and 1991. The distributions of Lp(a) levels were skewed to the right, and females were more likely than males to have Lp(a) levels greater than 30 mg/dl (14.3% versus 11.6%,
P<0.05). The Lp(a) level increased with age. Socioeconomic status did not seem to have consistent influence on the level of Lp(a). Smoking and alcohol use also had no effect on Lp(a) levels. Multivariate analysis indicated that older age and high level of low-density-lipoprotein cholesterol corresponded to an elevated Lp(a) level, while hypertriglyceridemia, low high-density-lipoprotein cholesterol level, obesity and high insulin resistance corresponded to a lower Lp(a) level. In univariate analysis, hyperinsulinemia was negatively associated with Lp(a) level (−0.107,
P<0.01) only in males. In females, use of oral contraceptive lowered Lp(a) levels, but menopause did not change Lp(a) levels. We also found that different correlation patterns existed for selected coagulation profiles between sexes. There was a significant correlation between Lp(a) and fibrinogen levels in males (0.154,
P<0.001) but not in females (0.007,
P>0.05). These data provided clues for investigating atherosclerotic risk factors and coagulation parameters for the Taiwanese population.</abstract><cop>Amsterdam</cop><pub>Elsevier Ireland Ltd</pub><pmid>10217355</pmid><doi>10.1016/S0021-9150(98)00298-6</doi><tpages>7</tpages><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0021-9150 |
| ispartof | Atherosclerosis, 1999-04, Vol.143 (2), p.267-273 |
| issn | 0021-9150 1879-1484 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69714795 |
| source | ScienceDirect Freedom Collection 2022-2024 |
| subjects | Adult Age Distribution Aged Analysis of Variance Arteriosclerosis - blood Arteriosclerosis - epidemiology Arteriosclerosis - etiology Atherosclerosis Atherosclerosis (general aspects, experimental research) Biological and medical sciences Blood and lymphatic vessels Cardiology. Vascular system Cardiovascular Diseases - blood Cardiovascular Diseases - epidemiology Cardiovascular Diseases - etiology Cohort Studies Female Health Surveys Humans Incidence Lipoprotein(a) Lipoprotein(a) - adverse effects Lipoprotein(a) - blood Lipoproteins - blood Male Medical sciences Middle Aged Multivariate Analysis Obesity - blood Obesity - epidemiology Population-based Risk Factors Sex Characteristics Socioeconomic Factors Taiwan - epidemiology Taiwanese |
| title | Lipoprotein (a) level in the population in Taiwan: relationship to sociodemographic and atherosclerotic risk factors |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-19T14%3A59%3A50IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Lipoprotein%20(a)%20level%20in%20the%20population%20in%20Taiwan:%20relationship%20to%20sociodemographic%20and%20atherosclerotic%20risk%20factors&rft.jtitle=Atherosclerosis&rft.au=Chien,%20Kuo-Liong&rft.date=1999-04-01&rft.volume=143&rft.issue=2&rft.spage=267&rft.epage=273&rft.pages=267-273&rft.issn=0021-9150&rft.eissn=1879-1484&rft_id=info:doi/10.1016/S0021-9150(98)00298-6&rft_dat=%3Cproquest_cross%3E69714795%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c503t-a51533a2303db38a5d69b2fac924eb08f130170d4ee78bd63d4dab87366cc2113%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=69714795&rft_id=info:pmid/10217355&rfr_iscdi=true |