Quality of Life and Parkinson's Disease

Background. People with Parkinson's disease (PD) have a progressive loss of function eventually leading to severe disability. Although PD would be expected to have a profound impact on an individual's psychosocial health, there is relatively limited research on its psychosocial effect. The...

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Bibliographic Details
Published in:The journals of gerontology. Series A, Biological sciences and medical sciences Biological sciences and medical sciences, 1999-04, Vol.54 (4), p.M197-M202
Main Authors: Koplas, Patricia A., Gans, Heidi B., Wisely, Mary P., Kuchibhatla, Maggie, Cutson, Toni M., Gold, Deborah T., Taylor, Carrie T., Schenkman, Margaret
Format: Article
Language:English
Subjects:
Activities of Daily Living
Aged
Aged, 80 and over
Attitude to Health
Cross-Sectional Studies
Depression - psychology
Disabled Persons
Disease Progression
Female
Forecasting
Gerontology
Humans
Internal-External Control
Male
Middle Aged
Motor Skills - physiology
Multivariate Analysis
Parkinson Disease - classification
Parkinson Disease - physiopathology
Parkinson Disease - psychology
Parkinson's disease
Quality of Life
Regression Analysis
Social Adjustment
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Summary:Background. People with Parkinson's disease (PD) have a progressive loss of function eventually leading to severe disability. Although PD would be expected to have a profound impact on an individual's psychosocial health, there is relatively limited research on its psychosocial effect. The purposes of this study were (a) to examine the relationships between physical disability, depression, and control beliefs and quality of life in people with PD and (b) to characterize how these psychosocial variables differ by stage of disease. Methods. Eighty-six individuals from five stages based on clinical disability, ages 51–87, were interviewed. Established instruments were used to measure physical disability, depression, and control beliefs. Quality of life (QOL) was rated on a 5-point Likert scale. Results. A multivariable regression model including physical disability, stage of disease, depression, mastery, and health locus of control predicted QOL (R2 = 0.48), with mastery as the only significant predictor (p = .0001). There were significant differences by PD stage for all variables (p < .05). Conclusions. Mastery predicted quality of life in individuals with PD even when depression and physical disability were included in the model. Differences in psychosocial variables by stage of PD suggest that the psychosocial profile of PD patients may change as the disease progresses.
ISSN:1079-5006
1758-535X
DOI:10.1093/gerona/54.4.M197