Delivery of a severely anaemic fetus after partial molar pregnancy: clinical and ultrasonographic findings

The incidence of a normal live fetus and a partial molar placenta is extremely rare. Although triploidy is the most frequent association, a fetus with normal karyotype can survive in cases of partial molar pregnancy. We report a case of partial molar placenta in which a live female baby was delivere...

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Bibliographic Details
Published in:Human reproduction (Oxford) 1999-04, Vol.14 (4), p.1122-1126
Main Authors: Hsieh, C.C., Hsieh, T.T., Hsueh, C., Kuo, D.M., Lo, L.M., Hung, T.H.
Format: Article
Language:English
Subjects:
Adult
Anemia - congenital
Biological and medical sciences
Diseases of mother, fetus and pregnancy
electronic fetal monitoring
Female
fetal anaemia
Gynecology. Andrology. Obstetrics
Humans
Hydatidiform Mole
Infant, Newborn
Infant, Premature
Medical sciences
partial molar pregnancy
Pregnancy
Pregnancy Complications, Neoplastic
Pregnancy. Fetus. Placenta
ultrasound
Uterine Neoplasms
β-human chorionic gonadotrophin
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Summary:The incidence of a normal live fetus and a partial molar placenta is extremely rare. Although triploidy is the most frequent association, a fetus with normal karyotype can survive in cases of partial molar pregnancy. We report a case of partial molar placenta in which a live female baby was delivered at 32 weeks gestation by a 30-year-old woman. At the 18th week, ultrasonographic examination revealed a normal fetus with a huge, multicystic placenta. Chromosomal evaluation by amniocentesis revealed a normal female karyotype (46,XX), and serial biometric measurement of the fetus showed normal growth during pregnancy. There were no obstetric complications until the 32nd gestational week when preterm rupture of the membranes occurred. The electronic fetal heart beat tracing showed a repeated sinusoid pattern and late deceleration after admission. The patient underwent emergency Caesarean section and delivered a 1551-g, anaemic female baby with an Apgar score of 1, 4 and 6 at 1, 5 and 10 min, respectively. The baby recovered within 2 weeks after respiratory support and transfusion of packed red blood cells. Although anaemia is one of the risk factors that jeopardize the fetus in the case of partial molar pregnancy, termination is not indicated when the fetus is normal and no complications have occurred.
ISSN:0268-1161
1460-2350
1460-2350
DOI:10.1093/humrep/14.4.1122