Microtubule dynamics: Controlling split ends

The rapid switching between growth and shrinkage at microtubule ends is important for many cellular processes. Recent studies on the structure of the microtubule and on the mechanism of action of the microtubule regulators XKCM1 and OP18 have revealed how these switching events are regulated.

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Bibliographic Details
Published in:Current biology 1999-04, Vol.9 (8), p.R274-R276
Main Author: McNally, Francis J.
Format: Article
Language:English
Subjects:
Guanosine Triphosphate - metabolism
Kinesin - metabolism
Microtubule Proteins
Microtubules - metabolism
Phosphoproteins - metabolism
Stathmin
Tubulin - metabolism
Xenopus Proteins
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Description
Summary:The rapid switching between growth and shrinkage at microtubule ends is important for many cellular processes. Recent studies on the structure of the microtubule and on the mechanism of action of the microtubule regulators XKCM1 and OP18 have revealed how these switching events are regulated.
ISSN:0960-9822
1879-0445
DOI:10.1016/S0960-9822(99)80177-8