Bench surgery with autotransplantation for bilateral synchronous Wilms' tumor: A report of three cases

The surgical management of bilateral synchronous nephroblastoma remains controversial. The authors describe three cases treated using ex vivo tumor dissection followed by autotransplantation in an attempt to preserve functioning renal tissue. Two children are alive and tumor free with adequate renal...

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Bibliographic Details
Published in:Journal of pediatric surgery 1999-04, Vol.34 (4), p.632-634
Main Authors: Desai, D., Nicholls, G., Duffy, P.G.
Format: Article
Language:English
Subjects:
Biological and medical sciences
Humans
Infant
Kidney Neoplasms - surgery
Kidney Transplantation - methods
Kidneys
Male
Medical sciences
Nephrology. Urinary tract diseases
Transplantation, Autologous
Tumors of the urinary system
Wilms Tumor - surgery
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Summary:The surgical management of bilateral synchronous nephroblastoma remains controversial. The authors describe three cases treated using ex vivo tumor dissection followed by autotransplantation in an attempt to preserve functioning renal tissue. Two children are alive and tumor free with adequate renal function at 30 months and 3 years, respectively. One died from tumor recurrence with metastases 9 months after surgery. This technique is an acceptable alternative to bilateral nephrectomy followed by transplantation.
ISSN:0022-3468
1531-5037
DOI:10.1016/S0022-3468(99)90092-1