Vestibular Neurectomy in the Guinea-pig: a Retrosigmoid Approach

The efferent cochlear system, composed of both ipsi- and contralateral bundles, runs along with the vestibular nerve and may serve as protection for the inner ear. Sectioning of the vestibular nerve could thus create an experimental model for further in-depth study of such a protective role. A perso...

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Bibliographic Details
Published in:Acta oto-laryngologica 1999-03, Vol.119 (2), p.171-173
Main Author: Maurizio Barbara, Giuseppe Attanasio, Federico Piccoli, Roberto Filipo
Format: Article
Language:English
Subjects:
Animals
Biological and medical sciences
Denervation - methods
Female
Guinea Pigs
Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics
Medical sciences
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the ear, the auditive nerve and the facial nerve
Vestibular Nerve - surgery
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Summary:The efferent cochlear system, composed of both ipsi- and contralateral bundles, runs along with the vestibular nerve and may serve as protection for the inner ear. Sectioning of the vestibular nerve could thus create an experimental model for further in-depth study of such a protective role. A personal surgical approach is described, involving a suboccipital (or retrosigmoid) route to the postero-medial aspect of the guinea-pig temporal bone, chosen because of its use for the induction of endolymphatic hydrops in the same species. The crucial step in this approach is the separation of the sigmoid sinus in its entirety, through an intra-dural access with a minimal removal/retraction of cerebellar tissue. This did not affect either the post-operative recovery of the animal or its hearing threshold level as assessed via auditory brainstem responses.
ISSN:0001-6489
1651-2251
DOI:10.1080/00016489950181602