Arachidonic acid amide inhibitors of gap junction cell-cell communication

A series of arachidonic acid amides including anandamide and arachidonamide that act as potent inhibitors of the rat glial cell gap junction is described.

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Bibliographic Details
Published in:Bioorganic & medicinal chemistry letters 1999-04, Vol.9 (8), p.1151-1154
Main Authors: Boger, Dale L., Sato, Haruhiko, Lerner, Aaron E., Guan, Xiaojun, Gilula, Norton B.
Format: Article
Language:English
Subjects:
Animals
Arachidonic Acid - chemical synthesis
Biological and medical sciences
Cell Communication - physiology
Gap Junctions - physiology
Medical sciences
Miscellaneous
Models, Chemical
Neuroglia - drug effects
Neuropharmacology
Pharmacology. Drug treatments
Rats
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Description
Summary:A series of arachidonic acid amides including anandamide and arachidonamide that act as potent inhibitors of the rat glial cell gap junction is described.
ISSN:0960-894X
1464-3405
DOI:10.1016/S0960-894X(99)00148-1