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A dynamic nuclear polarization strategy for multi-dimensional Earth’s field NMR spectroscopy
Dynamic nuclear polarization (DNP) is introduced as a powerful tool for polarization enhancement in multi-dimensional Earth’s field NMR spectroscopy. Maximum polarization enhancements, relative to thermal equilibrium in the Earth’s magnetic field, are calculated theoretically and compared to the mor...
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Published in: | Journal of magnetic resonance (1997) 2008-12, Vol.195 (2), p.162-168 |
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Main Authors: | , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
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Summary: | Dynamic nuclear polarization (DNP) is introduced as a powerful tool for polarization enhancement in multi-dimensional Earth’s field NMR spectroscopy. Maximum polarization enhancements, relative to thermal equilibrium in the Earth’s magnetic field, are calculated theoretically and compared to the more traditional prepolarization approach for NMR sensitivity enhancement at ultra-low fields. Signal enhancement factors on the order of 3000 are demonstrated experimentally using DNP with a nitroxide free radical, TEMPO, which contains an unpaired electron which is strongly coupled to a neighboring
14N nucleus via the hyperfine interaction. A high-quality 2D
19F–
1H COSY spectrum acquired in the Earth’s magnetic field with DNP enhancement is presented and compared to simulation. |
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ISSN: | 1090-7807 1096-0856 |
DOI: | 10.1016/j.jmr.2008.09.007 |