Serum concentrations of adiponectin and resistin in hyperthyroid Graves’ disease patients

This study was undertaken to determine whether serum adiponectin and resistin levels are influenced by hyperthyroidism and autoimmune factors and to find out whether their levels are dependent on the presence of ophthalmopathy. We measured serum concentrations of adiponectin and resistin in 76 patie...

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Bibliographic Details
Published in:Journal of endocrinological investigation 2008-09, Vol.31 (9), p.745-749
Main Authors: Sieminska, L., Niedziolka, D., Pillich, A., Kos-Kudla, B., Marek, B., Nowak, M., Borgiel-Marek, H.
Format: Article
Language:English
Subjects:
Adiponectin - blood
Autoantibodies - blood
Endocrinology
Female
Graves Ophthalmopathy - blood
Humans
Male
Medicine
Medicine & Public Health
Metabolic Diseases
Middle Aged
Original Articles
Regression Analysis
Resistin - blood
Thyrotropin - blood
Thyroxine - blood
Triiodothyronine - blood
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Summary:This study was undertaken to determine whether serum adiponectin and resistin levels are influenced by hyperthyroidism and autoimmune factors and to find out whether their levels are dependent on the presence of ophthalmopathy. We measured serum concentrations of adiponectin and resistin in 76 patients (63 women, 13 men) with Graves’ disease (GD) and compared them with levels of the control group which consisted of 30 healthy subjects. Patients were separated into two groups according to the presence or the absence of thyroid-associated ophthalmopathy (TAO). TAO (−) group consisted of 26 subjects without eye signs of GD and TAO (+) group included 50 subjects with ophthalmopathy. The latter group was further divided into 2 subgroups: with active TAO [26 patients, clinical activity score (CAS)≥4] and with inactive TAO (24 patients, CAS
ISSN:0391-4097
1720-8386
DOI:10.1007/BF03349251