Extramedullary hematopoiesis: findings on computed tomography scans of the chest in 6 patients

To present findings on computed tomography scans of the chest indicative of extramedullary hematopoiesis in six patients. We retrospectively analyzed computed tomography scans of six adult patients - five males and one female - with a mean age of 36.5 years. Two radiologists independently reviewed t...

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Bibliographic Details
Published in:Jornal brasileiro de pneumologia 2008-10, Vol.34 (10), p.812-816
Main Authors: Marchiori, Edson, Escuissato, Dante Luiz, Irion, Klaus Loureiro, Zanetti, Gláucia, Rodrigues, Rosana Souza, Meirelles, Gustavo de Souza Portes, Hochhegger, Bruno
Format: Article
Language:eng ; por
Subjects:
Adult
Anemia, Sickle Cell - diagnostic imaging
Diagnosis, Differential
Female
Hematopoiesis, Extramedullary - physiology
Humans
Male
Mediastinum - diagnostic imaging
Mediastinum - physiology
Middle Aged
Retrospective Studies
Thalassemia - diagnostic imaging
Tomography, X-Ray Computed - methods
Young Adult
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Summary:To present findings on computed tomography scans of the chest indicative of extramedullary hematopoiesis in six patients. We retrospectively analyzed computed tomography scans of six adult patients - five males and one female - with a mean age of 36.5 years. Two radiologists independently reviewed the scans, and a consensus was reached in discrepant cases. The most common finding in the scans was lower paravertebral masses with heterogeneous content (four patients). The scans of two patients showed a solitary parietal and pleural mass. There are findings in computed tomography scans that are highly suggestive of extramedullary hematopoiesis, especially when those findings correlate with underlying blood diseases. Such findings, in most of the cases, allow physicians to dispense with histopathological confirmation.
ISSN:1806-3756
DOI:10.1590/s1806-37132008001000009