Levosimendan and severe pulmonary hypertension during open heart surgery

Weaning from cardiopulmonary bypass is the most important stage during mitral valve surgery, especially in patients with severe pulmonary hypertension. We report two patients with severe pulmonary hypertension who were operated on because of valvular heart disease. To reduce the pulmonary artery pre...

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Bibliographic Details
Published in:General thoracic and cardiovascular surgery 2008-11, Vol.56 (11), p.563-565
Main Authors: Cicekcioglu, Ferit, Parlar, Ali Ihsan, Ersoy, Ozgur, Yay, Kerem, Hijazi, Alaa, Katircioglu, S. Fehmi
Format: Article
Language:English
Subjects:
Cardiac Surgery
Cardiac Surgical Procedures
Cardiology
Case Report
Female
Follow-Up Studies
Heart Valve Diseases - surgery
Heart Valve Prosthesis Implantation
Humans
Hydrazones - administration & dosage
Hydrazones - therapeutic use
Hypertension, Pulmonary - drug therapy
Medicine
Medicine & Public Health
Middle Aged
Pyridazines - administration & dosage
Pyridazines - therapeutic use
Surgical Oncology
Thoracic Surgery
Time Factors
Treatment Outcome
Vasodilator Agents - administration & dosage
Vasodilator Agents - therapeutic use
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Summary:Weaning from cardiopulmonary bypass is the most important stage during mitral valve surgery, especially in patients with severe pulmonary hypertension. We report two patients with severe pulmonary hypertension who were operated on because of valvular heart disease. To reduce the pulmonary artery pressure, levosimendan was used because of its vasodilatory and cytoprotective effects. All patients tolerated the operation and levosimendan administration. Their postoperative course was uneventful. Levosimendan can be used to treat pulmonary hypertension during operations for heart valve disease. Patients clearly benefit from the vasodilator action of the drug for reducing pulmonary artery pressure.
ISSN:1863-6705
1863-6713
DOI:10.1007/s11748-008-0301-4