Ictal paresis associated to PLEDS in two children: A video-EEG study

• Published in: Seizure (London, England) England), 2008-12, Vol.17 (8), p.735-739
• Main Authors: Calarese, Tiziana, Ferlazzo, Edoardo, Daquin, Geraldine, Genton, Pierre, Di Bella, Paolo, Villeneuve, Nathalie
• Format: Article
• Language: English
• Subjects: Child; Child, Preschool; Children; Electroencephalography - methods; Epilepsies, Partial - diagnosis; Epilepsies, Partial - etiology; Humans; Ictal paresis; Male; Neurology; Paresis - complications; PLEDs; Video Recording - methods; Video-EEG
• ISSN: 1059-1311; 1532-2688
• DOI: 10.1016/j.seizure.2008.04.002

Summary Ictal paresis (IP) is a rare negative motor phenomenon presenting challenging differential diagnostic problems with transient ischemic attacks, post-ictal paralysis, migraine and psychogenic paralysis. Video-EEG undoubtedly represents the essential mean for a proper diagnosis. Periodic lateralised epileptiform discharges (PLEDs) are a distinctive EEG pattern, consisting of periodic spike or sharp wave discharges, often associated with seizures. It is under debate if PLEDs should be considered only a peri-ictal or also an ictal EEG pattern. We describe two children with severe focal epilepsies, who presented IP recorded during video-EEG monitoring, associated to PLEDs. Clinical observation along with interictal and ictal scalp-EEG findings, suggested a fronto-temporal seizure onset in the first, and a temporo-insular onset in the second. We confirm that PLEDs may be an ictal pattern associated with negative motor phenomena.