Crosstalk among Histone Modifications

Histone modifications play a complex role in the regulation of transcription. Recent studies ( Duncan et al., 2008; Lee et al., 2007; Li et al., 2008) reveal that regulation of histone modifications can be functionally linked to reinforce the activation or repression of gene expression.

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Bibliographic Details
Published in:Cell 2008-11, Vol.135 (4), p.604-607
Main Authors: Suganuma, Tamaki, Workman, Jerry L.
Format: Article
Language:English
Subjects:
Animals
Chromosomes - metabolism
DNA-Directed RNA Polymerases - metabolism
Drosophila
Gene Expression
Histones - chemistry
Histones - metabolism
Humans
Mice
Models, Biological
Protein Processing, Post-Translational
Saccharomyces cerevisiae - metabolism
Schizosaccharomyces - metabolism
Transcription, Genetic
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Description
Summary:Histone modifications play a complex role in the regulation of transcription. Recent studies ( Duncan et al., 2008; Lee et al., 2007; Li et al., 2008) reveal that regulation of histone modifications can be functionally linked to reinforce the activation or repression of gene expression.
ISSN:0092-8674
1097-4172
DOI:10.1016/j.cell.2008.10.036