Vasculitis-like syndrome associated with Borrelia lusitaniae infection

We report the isolation of Borrelia lusitaniae from a 13-year-old female child presenting with a vasculitis syndrome. The patient was treated with doxycycline, 100 mg bid for 20 days, and is in remission after a follow-up of 2 years. These results should alert clinicians to the fact that B. lusitani...

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Bibliographic Details
Published in:Clinical rheumatology 2008-12, Vol.27 (12), p.1587-1591
Main Authors: Lopes de Carvalho, I., Fonseca, J. E., Marques, J. G., Ullmann, A., Hojgaard, A., Zeidner, N., Núncio, M. S.
Format: Article
Language:English
Subjects:
Adolescent
Animal vaccines
Anti-Bacterial Agents - therapeutic use
Borrelia - genetics
Borrelia - immunology
Borrelia - isolation & purification
Case Report
Doxycycline - therapeutic use
Female
Genotype
Humans
Immunoglobulin G
Immunoglobulin M
Lyme Disease - complications
Lyme Disease - diagnosis
Lyme Disease - drug therapy
Medicine
Medicine & Public Health
Molecular Sequence Data
Portugal
Rheumatology
Vasculitis - drug therapy
Vasculitis - microbiology
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Summary:We report the isolation of Borrelia lusitaniae from a 13-year-old female child presenting with a vasculitis syndrome. The patient was treated with doxycycline, 100 mg bid for 20 days, and is in remission after a follow-up of 2 years. These results should alert clinicians to the fact that B. lusitaniae may be pathogenic in humans, highlighting that patients may be seronegative or present with minimal positive antibody titres and clinical signs that are not specific for Lyme borreliosis. In order to prevent the occurrence of more serious disease manifestations via timely treatment, the analysis by molecular methods may be a useful approach when antibody titres are uninformative.
ISSN:0770-3198
1434-9949
DOI:10.1007/s10067-008-1012-z