Inclusion body myositis long after dermatomyositis : A report of two cases

Dermatomyositis, polymyositis, and inclusion body myositis are rare illnesses which appear to be distinct in clinical and pathologic features, pathogenesis, natural history, and response to therapy. We report two patients who first developed dermatomyositis, and then, after a disease-free interval o...

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Bibliographic Details
Published in:Clinical and experimental rheumatology 1999-03, Vol.17 (2), p.235-239
Main Authors: MCCOY, A. L, BUBB, M. R, PLOTZ, P. H, DAVIS, J. C
Format: Article
Language:English
Subjects:
Adult
Azathioprine - therapeutic use
Biological and medical sciences
Creatine Kinase - blood
Dermatomyositis - complications
Dermatomyositis - drug therapy
Dermatomyositis - enzymology
Dermatomyositis - pathology
Humans
Male
Medical sciences
Middle Aged
Muscle, Skeletal - pathology
Myositis, Inclusion Body - complications
Myositis, Inclusion Body - drug therapy
Myositis, Inclusion Body - enzymology
Myositis, Inclusion Body - pathology
Prednisolone - therapeutic use
Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis
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Summary:Dermatomyositis, polymyositis, and inclusion body myositis are rare illnesses which appear to be distinct in clinical and pathologic features, pathogenesis, natural history, and response to therapy. We report two patients who first developed dermatomyositis, and then, after a disease-free interval of many years, developed inclusion body myositis. This may have useful therapeutic implications for patients with dermatomyositis whose illness bocomes refractory to treatment.
ISSN:0392-856X
1593-098X