A study of the aetiology of pseudopregnancy in the bitch and the effect of cabergoline therapy

Thirty-two permanently pseudopregnant bitches were treated with the anti-prolactin drug cabergoline. They had all been ovariohysterectomised up to five months after their last season, in some cases over two years previously, when most were reported as showing no signs of the condition. The clinical...

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Bibliographic Details
Published in:Veterinary record 1999-04, Vol.144 (16), p.433-436
Main Authors: Harvey, M. J. A, Dale, M. J., Lindley, S., Waterston, M. M.
Format: Article
Language:English
Subjects:
Aggression - drug effects
Animals
Cabergoline
Dogs
Dopamine Agonists - pharmacology
Dopamine Agonists - therapeutic use
Ergolines - pharmacology
Ergolines - therapeutic use
Female
Lactation - drug effects
Prolactin - blood
Pseudopregnancy - drug therapy
Pseudopregnancy - veterinary
Treatment Outcome
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Summary:Thirty-two permanently pseudopregnant bitches were treated with the anti-prolactin drug cabergoline. They had all been ovariohysterectomised up to five months after their last season, in some cases over two years previously, when most were reported as showing no signs of the condition. The clinical signs were mainly behavioural, the majority being aggressive, and a small number were lactating. The efficiency of the cabergoline therapy was classified by the owners as ‘excellent’ or ‘good’ in 50 per cent of the cases, and fair in 36 per cent. The rate of success was markedly better than in similar cases treated with reproductive steroids. In all but one of the bitches, the plasma prolactin concentrations were basal.
ISSN:0042-4900
2042-7670
DOI:10.1136/vr.144.16.433