Electron microscopic observation on the parathyroid gland of the cardiomyopathic hamster (UM-X7.1 Syrian hamster)

The ultrastructure of the parathyroid gland (PTG) of the UM-X7.1 cardiomyopathic hamster (the UM-X7.1) was qualitatively and quantitatively compared with that of the normal hamster. In the UM-X7.1, the Golgi apparatus and rER were well developed compared with those of the control hamster. Morphometr...

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Bibliographic Details
Published in:Journal of electron microscopy 1999, Vol.48 (2), p.139-145
Main Authors: Utsumi, Michiya, Moriguchi, Keiichi, Takahashi, Hisahide, Kinoshita, Chiemi, Togari, Akifumi, Mizutani, Makoto, Ohno, Norikazu
Format: Article
Language:English
Subjects:
Animals
Calcium - blood
cardiomyopathy
Cardiomyopathy, Dilated - pathology
Cricetinae
Disease Models, Animal
Endoplasmic Reticulum, Rough - ultrastructure
Golgi Apparatus - ultrastructure
Male
Mesocricetus
Microscopy, Electron
morphometry
NIH Image programme
Organelles - ultrastructure
parathyroid gland
Parathyroid Glands - ultrastructure
ultrastructure
UM-X7.1 Syrian hamster
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Summary:The ultrastructure of the parathyroid gland (PTG) of the UM-X7.1 cardiomyopathic hamster (the UM-X7.1) was qualitatively and quantitatively compared with that of the normal hamster. In the UM-X7.1, the Golgi apparatus and rER were well developed compared with those of the control hamster. Morphometric analysis revealed that the mean values of the Golgi apparatus, rER and large vacuolar bodies were significantly greater in the UM-X7.1 than in the normal hamster and the mean value of lipid droplets was significantly less in the UM-X7.1 than in the normal hamster. Ultrastructurally, we consider that in the UM-X7.1, the synthesis and release of the parathyroid hormone may be activated by an excessive amount of circulating catecholamine, and the functional activity of the PTG may be higher than that in the normal hamster.
ISSN:0022-0744
1477-9986
DOI:10.1093/oxfordjournals.jmicro.a023660