Treatment experiences of testicular cancer in Hispanic patients with Down’s syndrome at the National Cancer Institute of Mexico

We present 4 case studies of patients with Down’s syndrome and testicular germ-cell cancer, treated with conventional methods at the National Cancer Institute of Mexico, with similar outcomes as patients without this syndrome. There are several reports of testicular cancer arising in patients with D...

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Bibliographic Details
Published in:Clinical & translational oncology 2008-11, Vol.10 (11), p.768-771
Main Authors: Aguilar-Ponce, José Luis, Vidal-Millán, Silvia, Molina-Calzada, Carlos, Chilaca-Rosas, Fátima, Martínez-Cedillo, Jorge, Cruz-López, Juan Carlos
Format: Article
Language:English
Subjects:
Abnormalities, Multiple
Antineoplastic Combined Chemotherapy Protocols - administration & dosage
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Bleomycin - administration & dosage
Brain Neoplasms - secondary
Case Reports
Cisplatin - administration & dosage
Combined Modality Therapy
Cryptorchidism - complications
Down Syndrome - complications
Etoposide - administration & dosage
Fatal Outcome
Humans
Lung Neoplasms - secondary
Lymphatic Metastasis
Male
Medicine
Medicine & Public Health
Mexico
Neoplasms, Germ Cell and Embryonal - complications
Neoplasms, Germ Cell and Embryonal - pathology
Neoplasms, Germ Cell and Embryonal - secondary
Neoplasms, Germ Cell and Embryonal - surgery
Oncology
Orchiectomy
Remission Induction
Retroperitoneal Neoplasms - radiotherapy
Retroperitoneal Neoplasms - secondary
Seminoma - complications
Seminoma - pathology
Seminoma - radiotherapy
Seminoma - surgery
Testicular Neoplasms - complications
Testicular Neoplasms - pathology
Testicular Neoplasms - surgery
Treatment Outcome
Young Adult
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Description
Summary:We present 4 case studies of patients with Down’s syndrome and testicular germ-cell cancer, treated with conventional methods at the National Cancer Institute of Mexico, with similar outcomes as patients without this syndrome. There are several reports of testicular cancer arising in patients with Down’s syndrome worldwide, mainly from Caucasian populations. We discuss some theories about the association and the possible increase of incidence.
ISSN:1699-048X
1699-3055
DOI:10.1007/s12094-008-0286-6