Moraxella bovis pathogenicity: An update

Abstract Moraxella bovis is the etiologic agent of infectious bovine keratoconjunctivitis, the most important ocular disease affecting cattle worldwide. The severity of the cases varied from eyes that exhibited mild signs to severe clinical cases with profuse lacrimation, conjunctival swelling, corn...

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Bibliographic Details
Published in:Comparative immunology, microbiology and infectious diseases microbiology and infectious diseases, 2008-11, Vol.31 (6), p.449-458
Main Authors: Postma, Gabriela Cintia, Carfagnini, Julio César, Minatel, Leonardo
Format: Article
Language:English
Subjects:
Allergy and Immunology
Animals
Bacteriology
Biological and medical sciences
Bétail
Cattle
Cattle Diseases - microbiology
Cattle Diseases - pathology
Cattle Diseases - transmission
Disease Susceptibility
Epithelium, Corneal - microbiology
Epithelium, Corneal - pathology
Fundamental and applied biological sciences. Psychology
Hemolysin Proteins - metabolism
Infectious bovine keratoconjunctivitis
Infectious Disease
Keratoconjunctivitis, Infectious - microbiology
Keratoconjunctivitis, Infectious - pathology
Keratoconjunctivitis, Infectious - transmission
Kérato-conjunctivite infectieuse bovine
Lysophospholipase - metabolism
Microbiology
Miscellaneous
Moraxella (Moraxella) bovis - enzymology
Moraxella (Moraxella) bovis - pathogenicity
Moraxella bovis
Moraxellaceae Infections - microbiology
Moraxellaceae Infections - transmission
Moraxellaceae Infections - veterinary
Pathogenesis
Pathogénie
Peptide Hydrolases - metabolism
Virulence
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Summary:Abstract Moraxella bovis is the etiologic agent of infectious bovine keratoconjunctivitis, the most important ocular disease affecting cattle worldwide. The severity of the cases varied from eyes that exhibited mild signs to severe clinical cases with profuse lacrimation, conjunctival swelling, corneal opacity, and ulceration. Although the mortality is low, there is a high morbidity and important economic loss in terms of significant reduction in production. This paper examines aspects such as the pathogenesis of the disease and the mechanisms by which this unique bacterium is able to disrupt the corneal epithelium and cause infection.
ISSN:0147-9571
1878-1667
DOI:10.1016/j.cimid.2008.04.001