Acute coronary syndromes: the clot is there

Attempts to extract clot from an infarct-related coronary artery have underestimated the frequency and pathophysiologic significance of thrombus in acute coronary syndromes. The overwhelming body of evidence garnered over the last 20 years, especially the achievement of reperfusion (Thrombolysis In...

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Bibliographic Details
Published in:The American journal of cardiology 1999-06, Vol.83 (11), p.1556-1557
Main Authors: Timmis, G C, White, H D
Format: Article
Language:English
Subjects:
Cardiovascular disease
Coronary Disease - complications
Coronary Thrombosis - complications
Editorials
Humans
Myocardial Infarction - therapy
Thrombolytic Therapy
Online Access:Get full text
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Summary:Attempts to extract clot from an infarct-related coronary artery have underestimated the frequency and pathophysiologic significance of thrombus in acute coronary syndromes. The overwhelming body of evidence garnered over the last 20 years, especially the achievement of reperfusion (Thrombolysis In Myocardial Infarction trial grade 2 and 3 flow) with most of the newer thrombolytic agents in >80% of cases, incontrovertibly establishes a critical role for thrombus in acute occlusive coronary artery disease.
ISSN:0002-9149
1879-1913
DOI:10.1016/S0002-9149(99)00147-2