Interest of ferulic acid ethyl ester in photoprotective creams: Measure of efficacy by in vitro method

Topical sunscreens have been used for many years on exposed areas to protect the skin from the damaging effects of ultraviolets. If the sunscreens were essential, it is suggested that they have adverse effects. We chose to study ferulic acid ethyl ester (FAEE) as agent which could potentially be use...

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Bibliographic Details
Published in:Natural product research 2008-11, Vol.22 (16), p.1467-1471
Main Authors: Choquenet, Benjamin, Couteau, Celine, Paparis, Eva, Coiffard, Laurence J.M.
Format: Article
Language:English
Subjects:
Algorithms
Coumaric Acids - pharmacology
Coumaric Acids - therapeutic use
Emollients - pharmacology
ferulic acid ethyl ester (FAEE)
PF-UVA
Photochemistry - methods
photostability
SPF
Sunlight - adverse effects
Sunscreening Agents - pharmacology
Sunscreening Agents - therapeutic use
Ultraviolet Rays - adverse effects
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Summary:Topical sunscreens have been used for many years on exposed areas to protect the skin from the damaging effects of ultraviolets. If the sunscreens were essential, it is suggested that they have adverse effects. We chose to study ferulic acid ethyl ester (FAEE) as agent which could potentially be used in sunscreen products. FAEE was incorporated at various concentrations into O/W emulsions. Total of 30 mg of product exactly weighed were spread on poly(methylmethacrylate) plates over the whole surface (25 cm 2 ). So, sun protection factor (SPF) and PF-UVA of the creams were measured in vitro. Transmission measurements between 290 and 400 nm were carried out using a spectrophotometer equipped with an integrating sphere. Incorporated in O/W creams, at a concentration of 10%, FAEE give a SPF similar to that of benzymidazilate, a filter permitted in EU.
ISSN:1478-6419
1478-6427
DOI:10.1080/14786410802144974