Better Survival With Statin Administration After Revascularization Therapy in Japanese Patients With Coronary Artery Disease: Perspectives From the CREDO-Kyoto Registry

Background The importance of statins in cardiovascular prevention has been demonstrated in various patient subsets. This study aimed to evaluate the effects of statins on long-term outcomes of Japanese patients undergoing their first coronary revascularization. Methods and Results A total of 9,225 p...

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Bibliographic Details
Published in:Circulation Journal 2008, Vol.72(12), pp.1937-1945
Main Authors: Furukawa, Yutaka, Taniguchi, Ryoji, Ehara, Natsuhiko, Ozasa, Neiko, Haruna, Yoshisumi, Saito, Naritatsu, Doi, Takahiro, Hoshino, Kozo, Shizuta, Satoshi, Morimoto, Takeshi, Imai, Yukiko, Teramukai, Satoshi, Fukushima, Masanori, Kita, Toru, Kimura, Takeshi, Investigators, CREDO-Kyoto
Format: Article
Language:English
Subjects:
Aged
Angioplasty, Balloon, Coronary - adverse effects
Angioplasty, Balloon, Coronary - mortality
Cardiovascular Diseases - etiology
Cardiovascular Diseases - mortality
Cardiovascular Diseases - prevention & control
Coronary Artery Bypass - adverse effects
Coronary Artery Bypass - mortality
Coronary artery disease
Coronary Artery Disease - mortality
Coronary Artery Disease - therapy
Female
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors - therapeutic use
Japan
Kaplan-Meier Estimate
Male
Mortality
Multivariate Analysis
Patient Discharge
Proportional Hazards Models
Registries
Retrospective Studies
Revascularization
Risk Assessment
Secondary Prevention
Statins
Time Factors
Treatment Outcome
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Summary:Background The importance of statins in cardiovascular prevention has been demonstrated in various patient subsets. This study aimed to evaluate the effects of statins on long-term outcomes of Japanese patients undergoing their first coronary revascularization. Methods and Results A total of 9,225 patients undergoing their first coronary revascularizations during 2000-2002 were divided into 2 groups according to the use of statins at discharge; patients with acute myocardial infarction were not included. Statins was administered to only 28.5% (n=2,630) of the patients. The median follow-up period was 3.5 years. Patients on statin therapy showed lower all-cause (5.2% vs 10.0%; p
ISSN:1346-9843
1347-4820
DOI:10.1253/circj.CJ-08-0293