The antiphospholipid syndrome

The antiphospholipid syndrome is an acquired autoimmune syndrome characterized by arterial and/or venous thrombosis and/or pregnancy morbidity in association with the prolonged presence of serum autoantibodies, including the so-called lupus anticoagulant and anticardiolipin antibodies, which are mai...

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Bibliographic Details
Published in:Best practice & research. Clinical rheumatology 2008-10, Vol.22 (5), p.831-845
Main Authors: Pasquali, Jean-Louis, MD, PhD, Poindron, Vincent, MD, Korganow, Anne-Sophie, MD, PhD, Martin, Thierry, MD, PhD
Format: Article
Language:English
Subjects:
Adult
anticardiolipin antibodies
antiphospholipid syndrome
Antiphospholipid Syndrome - blood
Antiphospholipid Syndrome - complications
Antiphospholipid Syndrome - diagnosis
Female
Humans
lupus anticoagulant
Pregnancy
Rheumatology
Young Adult
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Description
Summary:The antiphospholipid syndrome is an acquired autoimmune syndrome characterized by arterial and/or venous thrombosis and/or pregnancy morbidity in association with the prolonged presence of serum autoantibodies, including the so-called lupus anticoagulant and anticardiolipin antibodies, which are mainly directed against complexes of proteins and anionic phospholipids.
ISSN:1521-6942
1532-1770
DOI:10.1016/j.berh.2008.08.008