A New Diagnostic Method for Early Gastric Cancer: Volume Measurement by 3-Dimensional Endoscopic Ultrasonography in Early Gastric Cancer and Its Clinical Significance

Background: The objective of the present study was to measure the volume of early gastric cancer using 3-dimensional endoscopic ultrasonography (3D-EUS) and to ascertain the clinical significance of this new diagnostic method. Patients and Methods: The study comprised 100 patients with early gastric...

Full description

Saved in:
Bibliographic Details
Published in:Anticancer research 2008-09, Vol.28 (5B), p.2907-2912
Main Authors: FUTAWATARI, Nobue, KIKUCHI, Shiro, SAKURAMOTO, Shinichi, KIDA, Mitsuhiro, WATANABE, Masahiko
Format: Article
Language:English
Subjects:
Adult
Aged
Aged, 80 and over
Biological and medical sciences
Endosonography - methods
Female
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Imaging, Three-Dimensional - methods
Intraoperative Care - methods
Lymph Nodes - diagnostic imaging
Lymph Nodes - pathology
Lymphatic Metastasis
Male
Medical sciences
Middle Aged
Stomach Neoplasms - diagnostic imaging
Stomach Neoplasms - pathology
Stomach Neoplasms - surgery
Stomach. Duodenum. Small intestine. Colon. Rectum. Anus
Tumors
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background: The objective of the present study was to measure the volume of early gastric cancer using 3-dimensional endoscopic ultrasonography (3D-EUS) and to ascertain the clinical significance of this new diagnostic method. Patients and Methods: The study comprised 100 patients with early gastric cancer who underwent preoperative 3D-EUS followed by surgical resection. The relationships of lymph node metastasis to 10 clinicopathological factors (gender, age, tumor location, ulcer, depth, macroscopic type, tumor histology, lymphatic invasion and venous invasion) and preoperative tumor volume (log tumor volume) as measured by 3D-EUS were determined. Results: Median tumor volume was 414.75 mm 3 (range, 7.8-2,683.8 mm 3 ) and median log tumor volume was 2.617 (range, 1.444-3.429). Univariate analyses showed that three factors (lymphatic invasion, p=0.0001; venous invasion, p=0.0216; log tumor volume, p=0.0121) correlated significantly with lymph node metastasis. Multivariate analysis showed only two factors (lymphatic invasion, p=0.011, regression coefficient=0.104; log tumor volume, p=0.020, regression coefficient=30.414) representing independent predictors for lymph node metastasis. Conclusion: Tumor volume as measured by 3D-EUS represents an independent risk factor for lymph node metastasis in early gastric cancer. This new method can be used as a reliable diagnostic tool for early gastric cancer.
ISSN:0250-7005
1791-7530