Responsiveness to stimuli of bispectral index, middle latency auditory evoked potentials and clinical scales in critically ill children

Summary We performed simultaneous recordings of Bispectral Index (BIS) and middle latency auditory evoked potentials. We also recorded two clinical scales, the Modified Ramsay scale and the COMFORT scale. Heart rate and blood pressure were measured once a day, for a maximum of 5 days, in 81 critical...

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Bibliographic Details
Published in:Anaesthesia 2008-12, Vol.63 (12), p.1296-1301
Main Authors: Lamas, A., López‐Herce, J., Sancho, L., Mencía, S., Carrillo, Á., José Santiago, M., Martínez, V.
Format: Article
Language:English
Subjects:
Acoustic Stimulation - methods
Adolescent
Anesthesia
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Anesthesiology
Awareness
Biological and medical sciences
Blood Pressure
Child
Child, Preschool
Conscious Sedation
Critical care
Critical Care - methods
Critical Illness - therapy
Electroencephalography
Evoked Potentials, Auditory
Female
Heart Rate
Humans
Infant
Infant, Newborn
Male
Measurement techniques
Medical sciences
Neuromuscular Blocking Agents - pharmacology
Pediatrics
Physical Stimulation - methods
Prospective Studies
Reaction Time
Respiration, Artificial
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Summary:Summary We performed simultaneous recordings of Bispectral Index (BIS) and middle latency auditory evoked potentials. We also recorded two clinical scales, the Modified Ramsay scale and the COMFORT scale. Heart rate and blood pressure were measured once a day, for a maximum of 5 days, in 81 critically ill children. Changes with tactile, auditory, and painful stimuli were analysed. All the stimuli significantly increased the BIS value, the painful stimulus having the greatest effect. The painful stimulus was the only one that altered the middle latency auditory evoked potentials. Although the responses of the clinical scales to stimuli were statistically significant, they were of little clinical relevance. None of the stimuli used significantly altered the heart rate or blood pressure. We conclude that tactile, auditory and painful stimuli produced changes of little relevance in the clinical scales, BIS or middle latency auditory evoked potentials. We found the BIS was the most sensitive method and the painful stimulus had the greatest effect.
ISSN:0003-2409
1365-2044
DOI:10.1111/j.1365-2044.2008.05654.x