Alternatives to allogeneic blood transfusions

ConclusionThe procurement of autologous blood is an accepted standard of care for elective surgery. However, the costs and potential complications, as well as the potential benefits of autologous blood procurement strategies, need to be reconsidered. In the future, blood conservation programs should...

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Bibliographic Details
Published in:Canadian journal of anaesthesia 1999-05, Vol.46 (5), p.R3-R9
Main Author: MONK, T. G
Format: Article
Language:English
Subjects:
Alternatives
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Blood Substitutes - therapeutic use
Blood Transfusion - economics
Blood Transfusion, Autologous - adverse effects
Blood Transfusion, Autologous - economics
Blood transfusions
Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis
Elective Surgical Procedures
Erythropoietin - therapeutic use
Hemodilution
Humans
Medical sciences
Recombinant Proteins
Transfusion Reaction
Transfusions. Complications. Transfusion reactions. Cell and gene therapy
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Summary:ConclusionThe procurement of autologous blood is an accepted standard of care for elective surgery. However, the costs and potential complications, as well as the potential benefits of autologous blood procurement strategies, need to be reconsidered. In the future, blood conservation programs should combine cost-effective blood procurement strategies, such as ANH, with interventions that stimulate preoperative erythropoiesis. When released for clinical use, the addition of oxygen-carrying solutions to these blood conservation techniques will, hopefully, eliminate allogeneic blood use.
ISSN:0832-610X
1496-8975
DOI:10.1007/bf03013177