Loading…
Local intramural heparin delivery during primary angioplasty for acute myocardial infarction: results of the Local PAMI Pilot Study
The feasibility and safety of local heparin delivery during acute infarct angioplasty was evaluated in a prospective, multicenter, 120-patient series. Angioplasty was performed using standard techniques, after which heparin (4,000 U) was delivered locally; 25% of patients received stents. Procedural...
Saved in:
| Published in: | Catheterization and cardiovascular interventions 1999-06, Vol.47 (2), p.237-242 |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Format: | Article |
| Language: | English |
| Subjects: | |
| Online Access: | Get full text |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| cited_by | |
|---|---|
| cites | |
| container_end_page | 242 |
| container_issue | 2 |
| container_start_page | 237 |
| container_title | Catheterization and cardiovascular interventions |
| container_volume | 47 |
| creator | Esente, P Kaplan, A V Ford, J K Martin, J L Ayres, M Kosinski, E J Lasorda, D M Graham, M Gallant, P Grines, L L Grines, C L |
| description | The feasibility and safety of local heparin delivery during acute infarct angioplasty was evaluated in a prospective, multicenter, 120-patient series. Angioplasty was performed using standard techniques, after which heparin (4,000 U) was delivered locally; 25% of patients received stents. Procedural success was reported in 98% of patients; 6.7% of patients suffered death, reinfarction, recurrent ischemia, or stroke during the index hospitalization. The 6-month target vessel revascularization rate was 12.5%. Local heparin therapy with provisional stenting in acute myocardial infarction patients is safe, feasible, associated with a low rate of infarct artery revascularization at 6 months, and may potentially eliminate the need for systemic heparin following the procedure. |
| doi_str_mv | 10.1002/(SICI)1522-726X(199906)47:2<237::AID-CCD24>3.0.CO;2-S |
| format | article |
| fullrecord | <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_proquest_miscellaneous_69834204</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>69834204</sourcerecordid><originalsourceid>FETCH-LOGICAL-p122t-51e56ff72b3c60ddfc352f92ac6536a9d4ce3bb4393aab13a89959fdc32e13623</originalsourceid><addsrcrecordid>eNo1kElLBDEQhXNQ3P-C5CR66DGpdKfNuMDQbg0jCqPgbUhn0UhvJmlhzv5xGx1P9R68-opXCF1SMqGEwOnxoizKE5oBJDnw12MqhCD8JM2ncAEsn05n5XVSFNeQXrEJmRSP55AsNtDO7wYVKd9GuyF8EEIEB7GFtilhOc8o20Hf807JGrs2etkMfpTvppfetVib2n0Zv8J6GO0b7r1r5Ghl--a6vpYhrrDtPJZqiAY3q5HjtftlWelVdF07xd6EoY4BdxbHd4P_jj3NHkr85Oou4kUc9GofbVpZB3Ownnvo5fbmubhP5o93ZTGbJz0FiElGTcatzaFiihOtrWIZWAFS8YxxKXSqDKuqlAkmZUWZPBMiE1YrBoYyDmwPHf1xe999DibEZeOCMnUtW9MNYcnFGUuBpGPwcB0cqsbo5br68v9t7AcECHif</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>69834204</pqid></control><display><type>article</type><title>Local intramural heparin delivery during primary angioplasty for acute myocardial infarction: results of the Local PAMI Pilot Study</title><source>Wiley-Blackwell Read & Publish Collection</source><creator>Esente, P ; Kaplan, A V ; Ford, J K ; Martin, J L ; Ayres, M ; Kosinski, E J ; Lasorda, D M ; Graham, M ; Gallant, P ; Grines, L L ; Grines, C L</creator><creatorcontrib>Esente, P ; Kaplan, A V ; Ford, J K ; Martin, J L ; Ayres, M ; Kosinski, E J ; Lasorda, D M ; Graham, M ; Gallant, P ; Grines, L L ; Grines, C L</creatorcontrib><description>The feasibility and safety of local heparin delivery during acute infarct angioplasty was evaluated in a prospective, multicenter, 120-patient series. Angioplasty was performed using standard techniques, after which heparin (4,000 U) was delivered locally; 25% of patients received stents. Procedural success was reported in 98% of patients; 6.7% of patients suffered death, reinfarction, recurrent ischemia, or stroke during the index hospitalization. The 6-month target vessel revascularization rate was 12.5%. Local heparin therapy with provisional stenting in acute myocardial infarction patients is safe, feasible, associated with a low rate of infarct artery revascularization at 6 months, and may potentially eliminate the need for systemic heparin following the procedure.</description><identifier>ISSN: 1522-1946</identifier><identifier>DOI: 10.1002/(SICI)1522-726X(199906)47:2<237::AID-CCD24>3.0.CO;2-S</identifier><identifier>PMID: 10376513</identifier><language>eng</language><publisher>United States</publisher><subject>Aged ; Angioplasty, Balloon, Coronary ; Feasibility Studies ; Female ; Fibrinolytic Agents - administration & dosage ; Heparin - administration & dosage ; Humans ; Infusions, Intra-Arterial ; Male ; Middle Aged ; Myocardial Infarction - therapy ; Pilot Projects ; Prospective Studies ; Stents ; Treatment Outcome</subject><ispartof>Catheterization and cardiovascular interventions, 1999-06, Vol.47 (2), p.237-242</ispartof><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10376513$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Esente, P</creatorcontrib><creatorcontrib>Kaplan, A V</creatorcontrib><creatorcontrib>Ford, J K</creatorcontrib><creatorcontrib>Martin, J L</creatorcontrib><creatorcontrib>Ayres, M</creatorcontrib><creatorcontrib>Kosinski, E J</creatorcontrib><creatorcontrib>Lasorda, D M</creatorcontrib><creatorcontrib>Graham, M</creatorcontrib><creatorcontrib>Gallant, P</creatorcontrib><creatorcontrib>Grines, L L</creatorcontrib><creatorcontrib>Grines, C L</creatorcontrib><title>Local intramural heparin delivery during primary angioplasty for acute myocardial infarction: results of the Local PAMI Pilot Study</title><title>Catheterization and cardiovascular interventions</title><addtitle>Catheter Cardiovasc Interv</addtitle><description>The feasibility and safety of local heparin delivery during acute infarct angioplasty was evaluated in a prospective, multicenter, 120-patient series. Angioplasty was performed using standard techniques, after which heparin (4,000 U) was delivered locally; 25% of patients received stents. Procedural success was reported in 98% of patients; 6.7% of patients suffered death, reinfarction, recurrent ischemia, or stroke during the index hospitalization. The 6-month target vessel revascularization rate was 12.5%. Local heparin therapy with provisional stenting in acute myocardial infarction patients is safe, feasible, associated with a low rate of infarct artery revascularization at 6 months, and may potentially eliminate the need for systemic heparin following the procedure.</description><subject>Aged</subject><subject>Angioplasty, Balloon, Coronary</subject><subject>Feasibility Studies</subject><subject>Female</subject><subject>Fibrinolytic Agents - administration & dosage</subject><subject>Heparin - administration & dosage</subject><subject>Humans</subject><subject>Infusions, Intra-Arterial</subject><subject>Male</subject><subject>Middle Aged</subject><subject>Myocardial Infarction - therapy</subject><subject>Pilot Projects</subject><subject>Prospective Studies</subject><subject>Stents</subject><subject>Treatment Outcome</subject><issn>1522-1946</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><recordid>eNo1kElLBDEQhXNQ3P-C5CR66DGpdKfNuMDQbg0jCqPgbUhn0UhvJmlhzv5xGx1P9R68-opXCF1SMqGEwOnxoizKE5oBJDnw12MqhCD8JM2ncAEsn05n5XVSFNeQXrEJmRSP55AsNtDO7wYVKd9GuyF8EEIEB7GFtilhOc8o20Hf807JGrs2etkMfpTvppfetVib2n0Zv8J6GO0b7r1r5Ghl--a6vpYhrrDtPJZqiAY3q5HjtftlWelVdF07xd6EoY4BdxbHd4P_jj3NHkr85Oou4kUc9GofbVpZB3Ownnvo5fbmubhP5o93ZTGbJz0FiElGTcatzaFiihOtrWIZWAFS8YxxKXSqDKuqlAkmZUWZPBMiE1YrBoYyDmwPHf1xe999DibEZeOCMnUtW9MNYcnFGUuBpGPwcB0cqsbo5br68v9t7AcECHif</recordid><startdate>199906</startdate><enddate>199906</enddate><creator>Esente, P</creator><creator>Kaplan, A V</creator><creator>Ford, J K</creator><creator>Martin, J L</creator><creator>Ayres, M</creator><creator>Kosinski, E J</creator><creator>Lasorda, D M</creator><creator>Graham, M</creator><creator>Gallant, P</creator><creator>Grines, L L</creator><creator>Grines, C L</creator><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>7X8</scope></search><sort><creationdate>199906</creationdate><title>Local intramural heparin delivery during primary angioplasty for acute myocardial infarction: results of the Local PAMI Pilot Study</title><author>Esente, P ; Kaplan, A V ; Ford, J K ; Martin, J L ; Ayres, M ; Kosinski, E J ; Lasorda, D M ; Graham, M ; Gallant, P ; Grines, L L ; Grines, C L</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-p122t-51e56ff72b3c60ddfc352f92ac6536a9d4ce3bb4393aab13a89959fdc32e13623</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Aged</topic><topic>Angioplasty, Balloon, Coronary</topic><topic>Feasibility Studies</topic><topic>Female</topic><topic>Fibrinolytic Agents - administration & dosage</topic><topic>Heparin - administration & dosage</topic><topic>Humans</topic><topic>Infusions, Intra-Arterial</topic><topic>Male</topic><topic>Middle Aged</topic><topic>Myocardial Infarction - therapy</topic><topic>Pilot Projects</topic><topic>Prospective Studies</topic><topic>Stents</topic><topic>Treatment Outcome</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Esente, P</creatorcontrib><creatorcontrib>Kaplan, A V</creatorcontrib><creatorcontrib>Ford, J K</creatorcontrib><creatorcontrib>Martin, J L</creatorcontrib><creatorcontrib>Ayres, M</creatorcontrib><creatorcontrib>Kosinski, E J</creatorcontrib><creatorcontrib>Lasorda, D M</creatorcontrib><creatorcontrib>Graham, M</creatorcontrib><creatorcontrib>Gallant, P</creatorcontrib><creatorcontrib>Grines, L L</creatorcontrib><creatorcontrib>Grines, C L</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>MEDLINE - Academic</collection><jtitle>Catheterization and cardiovascular interventions</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Esente, P</au><au>Kaplan, A V</au><au>Ford, J K</au><au>Martin, J L</au><au>Ayres, M</au><au>Kosinski, E J</au><au>Lasorda, D M</au><au>Graham, M</au><au>Gallant, P</au><au>Grines, L L</au><au>Grines, C L</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Local intramural heparin delivery during primary angioplasty for acute myocardial infarction: results of the Local PAMI Pilot Study</atitle><jtitle>Catheterization and cardiovascular interventions</jtitle><addtitle>Catheter Cardiovasc Interv</addtitle><date>1999-06</date><risdate>1999</risdate><volume>47</volume><issue>2</issue><spage>237</spage><epage>242</epage><pages>237-242</pages><issn>1522-1946</issn><abstract>The feasibility and safety of local heparin delivery during acute infarct angioplasty was evaluated in a prospective, multicenter, 120-patient series. Angioplasty was performed using standard techniques, after which heparin (4,000 U) was delivered locally; 25% of patients received stents. Procedural success was reported in 98% of patients; 6.7% of patients suffered death, reinfarction, recurrent ischemia, or stroke during the index hospitalization. The 6-month target vessel revascularization rate was 12.5%. Local heparin therapy with provisional stenting in acute myocardial infarction patients is safe, feasible, associated with a low rate of infarct artery revascularization at 6 months, and may potentially eliminate the need for systemic heparin following the procedure.</abstract><cop>United States</cop><pmid>10376513</pmid><doi>10.1002/(SICI)1522-726X(199906)47:2<237::AID-CCD24>3.0.CO;2-S</doi><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 1522-1946 |
| ispartof | Catheterization and cardiovascular interventions, 1999-06, Vol.47 (2), p.237-242 |
| issn | 1522-1946 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69834204 |
| source | Wiley-Blackwell Read & Publish Collection |
| subjects | Aged Angioplasty, Balloon, Coronary Feasibility Studies Female Fibrinolytic Agents - administration & dosage Heparin - administration & dosage Humans Infusions, Intra-Arterial Male Middle Aged Myocardial Infarction - therapy Pilot Projects Prospective Studies Stents Treatment Outcome |
| title | Local intramural heparin delivery during primary angioplasty for acute myocardial infarction: results of the Local PAMI Pilot Study |
| url | http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-05T01%3A01%3A06IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Local%20intramural%20heparin%20delivery%20during%20primary%20angioplasty%20for%20acute%20myocardial%20infarction:%20results%20of%20the%20Local%20PAMI%20Pilot%20Study&rft.jtitle=Catheterization%20and%20cardiovascular%20interventions&rft.au=Esente,%20P&rft.date=1999-06&rft.volume=47&rft.issue=2&rft.spage=237&rft.epage=242&rft.pages=237-242&rft.issn=1522-1946&rft_id=info:doi/10.1002/(SICI)1522-726X(199906)47:2%3C237::AID-CCD24%3E3.0.CO;2-S&rft_dat=%3Cproquest_pubme%3E69834204%3C/proquest_pubme%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-p122t-51e56ff72b3c60ddfc352f92ac6536a9d4ce3bb4393aab13a89959fdc32e13623%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=69834204&rft_id=info:pmid/10376513&rfr_iscdi=true |