Co-receptors on B lymphocytes

Co-receptors have been shown to regulate the antigenreceptor signaling threshold for B cell responses by modulating the activation of signaling molecules that are essential for transmitting a signal through the antigen-receptor. Co-receptors appear to modulate the signaling threshold for B cell tole...

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Bibliographic Details
Published in:Current opinion in immunology 1999-06, Vol.11 (3), p.249-255
Main Author: Tsubata, Takeshi
Format: Article
Language:English
Subjects:
Animals
Antigens, CD - metabolism
Antigens, CD19 - metabolism
Antigens, Differentiation, B-Lymphocyte - metabolism
B-Lymphocytes - immunology
Cell Adhesion Molecules
Humans
Immune Tolerance
Lectins
Lymphocyte Activation
Phosphoric Monoester Hydrolases - metabolism
Receptors, Antigen, B-Cell - metabolism
Receptors, Complement 3d - metabolism
Receptors, IgG - metabolism
Sialic Acid Binding Ig-like Lectin 2
Signal Transduction - immunology
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Description
Summary:Co-receptors have been shown to regulate the antigenreceptor signaling threshold for B cell responses by modulating the activation of signaling molecules that are essential for transmitting a signal through the antigen-receptor. Co-receptors appear to modulate the signaling threshold for B cell tolerance distinctly from that for B cell activation.
ISSN:0952-7915
1879-0372
DOI:10.1016/S0952-7915(99)80041-7