Effect of Bupivacaine on Pain after Tonsillectomy: a Randomized Clinical Trial

Several authors have found that pre-incisional injection of local anaesthetics reduces postoperative pain. In the present double-blind study, comprising 126 inpatients aged 6-42 (mean 19) years, we investigated whether pre-incisional injection of bupivacaine during general anaesthesia reduces the pa...

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Bibliographic Details
Published in:Acta oto-laryngologica 1999, Vol.119 (3), p.369-376
Main Author: Stein Helge Glad Nordahl, Grethe Albrektsen, Anne Berit Guttormsen, Ib Lind Pedersen, Hans-Johan Breidablikk
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Factors
Anesthetics, Local - therapeutic use
Biological and medical sciences
Bupivacaine - therapeutic use
Child
Double-Blind Method
Ent. Stomatology
Female
Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics
Humans
Male
Medical sciences
Pain, Postoperative - drug therapy
Pharmacology. Drug treatments
Prospective Studies
Sex Factors
Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases
Surgery of the upper aerodigestive tract
Time Factors
Tonsillectomy
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Summary:Several authors have found that pre-incisional injection of local anaesthetics reduces postoperative pain. In the present double-blind study, comprising 126 inpatients aged 6-42 (mean 19) years, we investigated whether pre-incisional injection of bupivacaine during general anaesthesia reduces the pain experienced after tonsillectomy. The patients were randomized into three treatment groups: 43 patients were injected with 5 ml of bupivacaine (2.5 mg/ml)+epinephrine (5
ISSN:0001-6489
1651-2251
DOI:10.1080/00016489950181413