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Effect of Bupivacaine on Pain after Tonsillectomy: a Randomized Clinical Trial
Several authors have found that pre-incisional injection of local anaesthetics reduces postoperative pain. In the present double-blind study, comprising 126 inpatients aged 6-42 (mean 19) years, we investigated whether pre-incisional injection of bupivacaine during general anaesthesia reduces the pa...
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| Published in: | Acta oto-laryngologica 1999, Vol.119 (3), p.369-376 |
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| Format: | Article |
| Language: | English |
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| cited_by | cdi_FETCH-LOGICAL-c431t-e171a0d6a9d6d4b71a6f1cf17115f5cb5b1611a689d5ddfb0ad8bd976c1fbf843 |
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| cites | cdi_FETCH-LOGICAL-c431t-e171a0d6a9d6d4b71a6f1cf17115f5cb5b1611a689d5ddfb0ad8bd976c1fbf843 |
| container_end_page | 376 |
| container_issue | 3 |
| container_start_page | 369 |
| container_title | Acta oto-laryngologica |
| container_volume | 119 |
| creator | Stein Helge Glad Nordahl, Grethe Albrektsen, Anne Berit Guttormsen, Ib Lind Pedersen, Hans-Johan Breidablikk |
| description | Several authors have found that pre-incisional injection of local anaesthetics reduces postoperative pain. In the present double-blind study, comprising 126 inpatients aged 6-42 (mean 19) years, we investigated whether pre-incisional injection of bupivacaine during general anaesthesia reduces the pain experienced after tonsillectomy. The patients were randomized into three treatment groups: 43 patients were injected with 5 ml of bupivacaine (2.5 mg/ml)+epinephrine (5 |
| doi_str_mv | 10.1080/00016489950181413 |
| format | article |
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In the present double-blind study, comprising 126 inpatients aged 6-42 (mean 19) years, we investigated whether pre-incisional injection of bupivacaine during general anaesthesia reduces the pain experienced after tonsillectomy. The patients were randomized into three treatment groups: 43 patients were injected with 5 ml of bupivacaine (2.5 mg/ml)+epinephrine (5</description><identifier>ISSN: 0001-6489</identifier><identifier>EISSN: 1651-2251</identifier><identifier>DOI: 10.1080/00016489950181413</identifier><identifier>PMID: 10380745</identifier><identifier>CODEN: AOLAAJ</identifier><language>eng</language><publisher>Stockholm: Informa UK Ltd</publisher><subject>Adolescent ; Adult ; Age Factors ; Anesthetics, Local - therapeutic use ; Biological and medical sciences ; Bupivacaine - therapeutic use ; Child ; Double-Blind Method ; Ent. Stomatology ; Female ; Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics ; Humans ; Male ; Medical sciences ; Pain, Postoperative - drug therapy ; Pharmacology. Drug treatments ; Prospective Studies ; Sex Factors ; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases ; Surgery of the upper aerodigestive tract ; Time Factors ; Tonsillectomy</subject><ispartof>Acta oto-laryngologica, 1999, Vol.119 (3), p.369-376</ispartof><rights>1999 Informa UK Ltd All rights reserved: reproduction in whole or part not permitted 1999</rights><rights>1999 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c431t-e171a0d6a9d6d4b71a6f1cf17115f5cb5b1611a689d5ddfb0ad8bd976c1fbf843</citedby><cites>FETCH-LOGICAL-c431t-e171a0d6a9d6d4b71a6f1cf17115f5cb5b1611a689d5ddfb0ad8bd976c1fbf843</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,4023,27922,27923,27924</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=1781513$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/10380745$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Stein Helge Glad Nordahl, Grethe Albrektsen, Anne Berit Guttormsen, Ib Lind Pedersen, Hans-Johan Breidablikk</creatorcontrib><title>Effect of Bupivacaine on Pain after Tonsillectomy: a Randomized Clinical Trial</title><title>Acta oto-laryngologica</title><addtitle>Acta Otolaryngol</addtitle><description>Several authors have found that pre-incisional injection of local anaesthetics reduces postoperative pain. In the present double-blind study, comprising 126 inpatients aged 6-42 (mean 19) years, we investigated whether pre-incisional injection of bupivacaine during general anaesthesia reduces the pain experienced after tonsillectomy. The patients were randomized into three treatment groups: 43 patients were injected with 5 ml of bupivacaine (2.5 mg/ml)+epinephrine (5</description><subject>Adolescent</subject><subject>Adult</subject><subject>Age Factors</subject><subject>Anesthetics, Local - therapeutic use</subject><subject>Biological and medical sciences</subject><subject>Bupivacaine - therapeutic use</subject><subject>Child</subject><subject>Double-Blind Method</subject><subject>Ent. Stomatology</subject><subject>Female</subject><subject>Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics</subject><subject>Humans</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Pain, Postoperative - drug therapy</subject><subject>Pharmacology. Drug treatments</subject><subject>Prospective Studies</subject><subject>Sex Factors</subject><subject>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</subject><subject>Surgery of the upper aerodigestive tract</subject><subject>Time Factors</subject><subject>Tonsillectomy</subject><issn>0001-6489</issn><issn>1651-2251</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>1999</creationdate><recordtype>article</recordtype><recordid>eNp9kEtPGzEUha0KVFLoD-gGeYHYTfHNjCeelg2N0oKEWoTS9eiOH8LIY6f2DFX66-uQVFAhsboPf-fI9xDyAdhHYIKdMcagrkTTcAYCKijfkAnUHIrplMMemWzeiw1wQN6ldL8ZG8HfkgNgpWCzik_I94UxWg40GPplXNkHlGi9psHTm9xQNIOOdBl8ss5lLvTrTxTpLXoVevtHKzp31luJji6jRXdE9g26pN_v6iH5-XWxnF8W1z--Xc0vrgtZlTAUGmaATNXYqFpVXR5qA9LkLXDDZcc7qCEvRaO4UqZjqESnmlktwXRGVOUhOd36rmL4Neo0tL1NUjuHXocxtXUjKphynkHYgjKGlKI27SraHuO6BdZuQmxfhJg1xzvzseu1eqbYppaBkx2AKZ9uInpp0xM3E8Affc63mPUmxB5_h-hUO-DahfhPU772jc__ye80uuFOYtTtfRijz_m-csRfoHKeKg</recordid><startdate>1999</startdate><enddate>1999</enddate><creator>Stein Helge Glad Nordahl, Grethe Albrektsen, Anne Berit Guttormsen, Ib Lind Pedersen, Hans-Johan Breidablikk</creator><general>Informa UK Ltd</general><general>Taylor & Francis</general><general>Taylor and Francis</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope><scope>8BM</scope></search><sort><creationdate>1999</creationdate><title>Effect of Bupivacaine on Pain after Tonsillectomy: a Randomized Clinical Trial</title><author>Stein Helge Glad Nordahl, Grethe Albrektsen, Anne Berit Guttormsen, Ib Lind Pedersen, Hans-Johan Breidablikk</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c431t-e171a0d6a9d6d4b71a6f1cf17115f5cb5b1611a689d5ddfb0ad8bd976c1fbf843</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>1999</creationdate><topic>Adolescent</topic><topic>Adult</topic><topic>Age Factors</topic><topic>Anesthetics, Local - therapeutic use</topic><topic>Biological and medical sciences</topic><topic>Bupivacaine - therapeutic use</topic><topic>Child</topic><topic>Double-Blind Method</topic><topic>Ent. Stomatology</topic><topic>Female</topic><topic>Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics</topic><topic>Humans</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Pain, Postoperative - drug therapy</topic><topic>Pharmacology. Drug treatments</topic><topic>Prospective Studies</topic><topic>Sex Factors</topic><topic>Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases</topic><topic>Surgery of the upper aerodigestive tract</topic><topic>Time Factors</topic><topic>Tonsillectomy</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Stein Helge Glad Nordahl, Grethe Albrektsen, Anne Berit Guttormsen, Ib Lind Pedersen, Hans-Johan Breidablikk</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><collection>ComDisDome</collection><jtitle>Acta oto-laryngologica</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Stein Helge Glad Nordahl, Grethe Albrektsen, Anne Berit Guttormsen, Ib Lind Pedersen, Hans-Johan Breidablikk</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Effect of Bupivacaine on Pain after Tonsillectomy: a Randomized Clinical Trial</atitle><jtitle>Acta oto-laryngologica</jtitle><addtitle>Acta Otolaryngol</addtitle><date>1999</date><risdate>1999</risdate><volume>119</volume><issue>3</issue><spage>369</spage><epage>376</epage><pages>369-376</pages><issn>0001-6489</issn><eissn>1651-2251</eissn><coden>AOLAAJ</coden><abstract>Several authors have found that pre-incisional injection of local anaesthetics reduces postoperative pain. In the present double-blind study, comprising 126 inpatients aged 6-42 (mean 19) years, we investigated whether pre-incisional injection of bupivacaine during general anaesthesia reduces the pain experienced after tonsillectomy. The patients were randomized into three treatment groups: 43 patients were injected with 5 ml of bupivacaine (2.5 mg/ml)+epinephrine (5</abstract><cop>Stockholm</cop><pub>Informa UK Ltd</pub><pmid>10380745</pmid><doi>10.1080/00016489950181413</doi><tpages>8</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0001-6489 |
| ispartof | Acta oto-laryngologica, 1999, Vol.119 (3), p.369-376 |
| issn | 0001-6489 1651-2251 |
| language | eng |
| recordid | cdi_proquest_miscellaneous_69841255 |
| source | Taylor and Francis:Jisc Collections:Taylor and Francis Read and Publish Agreement 2024-2025:Medical Collection (Reading list) |
| subjects | Adolescent Adult Age Factors Anesthetics, Local - therapeutic use Biological and medical sciences Bupivacaine - therapeutic use Child Double-Blind Method Ent. Stomatology Female Head and neck surgery. Maxillofacial surgery. Dental surgery. Orthodontics Humans Male Medical sciences Pain, Postoperative - drug therapy Pharmacology. Drug treatments Prospective Studies Sex Factors Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases Surgery of the upper aerodigestive tract Time Factors Tonsillectomy |
| title | Effect of Bupivacaine on Pain after Tonsillectomy: a Randomized Clinical Trial |
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