Serial magnetic resonance imaging of cerebral atrophy in preclinical Alzheimer's disease

Quantitative cross-sectional magnetic resonance imaging studies of Alzheimer's disease have shown that atrophy is already present even in mildly affected people. However, single measures of structures with a wide normal range are not as sensitive as repeated measures in progressive disorders li...

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Bibliographic Details
Published in:The Lancet (British edition) 1999-06, Vol.353 (9170), p.2125-2125
Main Authors: Fox, Nick C, Warrington, Elizabeth K, Rossor, Martin N
Format: Article
Language:English
Subjects:
Alzheimer Disease - genetics
Alzheimer Disease - pathology
Alzheimer's disease
Biological and medical sciences
Brain - pathology
Case-Control Studies
Female
Humans
Investigative techniques, diagnostic techniques (general aspects)
Magnetic Resonance Imaging - methods
Medical research
Medical sciences
Middle Aged
Nervous system
NMR
Nuclear magnetic resonance
Prospective Studies
Radiodiagnosis. Nmr imagery. Nmr spectrometry
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Description
Summary:Quantitative cross-sectional magnetic resonance imaging studies of Alzheimer's disease have shown that atrophy is already present even in mildly affected people. However, single measures of structures with a wide normal range are not as sensitive as repeated measures in progressive disorders like Alzheimer's disease.
ISSN:0140-6736
1474-547X
DOI:10.1016/S0140-6736(99)00496-1