DNA repair: Rad52 – the means to an end

In eukaryotic organisms, double-strand breaks in chromosomal DNA are repaired either by non-homologous end-joining, or by homologous recombination. How do cells choose which pathway to use?

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Bibliographic Details
Published in:Current biology 1999-06, Vol.9 (12), p.R446-R448
Main Author: Hiom, Kevin
Format: Article
Language:English
Subjects:
Animals
DNA - genetics
DNA - metabolism
DNA Damage
DNA Repair - genetics
DNA Repair - physiology
DNA-Binding Proteins - metabolism
Models, Biological
Recombination, Genetic
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Description
Summary:In eukaryotic organisms, double-strand breaks in chromosomal DNA are repaired either by non-homologous end-joining, or by homologous recombination. How do cells choose which pathway to use?
ISSN:0960-9822
1879-0445
DOI:10.1016/S0960-9822(99)80278-4