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The NCEP-ATPIII but not the IDF criteria for the metabolic syndrome identify Type 2 diabetic patients at increased risk of chronic kidney disease
Aim To examine the association between chronic kidney disease (CKD) and the metabolic syndrome (MetS) using both International Diabetes Federation (IDF) and National Cholesterol Education Program's Adult Treatment Panel III (NCEP‐ATPIII) definitions in Chinese subjects with Type 2 diabetes. Me...
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| Published in: | Diabetic medicine 2008-12, Vol.25 (12), p.1419-1425 |
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| creator | Luk, A. O. Y. Ma, R. C. W. So, W-Y. Yang, X-L. Kong, A. P. S. Ozaki, R. Ko, G. T. C. Chow, C-C. Cockram, C. S. Chan, J. C. N. Tong, P. C. Y. |
| description | Aim To examine the association between chronic kidney disease (CKD) and the metabolic syndrome (MetS) using both International Diabetes Federation (IDF) and National Cholesterol Education Program's Adult Treatment Panel III (NCEP‐ATPIII) definitions in Chinese subjects with Type 2 diabetes.
Methods Subjects with Type 2 diabetes were categorized according to the presence or absence of MetS by IDF or NCEP‐ATPIII criteria. CKD was considered present if glomerular filtration rate, calculated using the abbreviated equation developed by the Modification of Diet in Renal Disease study with Chinese modification, was |
| doi_str_mv | 10.1111/j.1464-5491.2008.02602.x |
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| fullrecord | <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_miscellaneous_69849972</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>69849972</sourcerecordid><originalsourceid>FETCH-LOGICAL-c4352-749219f3f0bc936828225485ecce69604b3937d0f609cd1d54c300df3faf0c193</originalsourceid><addsrcrecordid>eNqNkctuEzEUhi0EoqHwCsgb2E3wbS5esKjStB3RhiKCWFoeX1Qncwm2IzKPwRvjaaKwxRtb53yfbZ0fAIjRHKf1aTPHrGBZzjieE4SqOSIFIvPDCzA7N16CGSoZySgq8QV4E8IGIUw45a_BBeaIFYShGfizfjJwtVg-Zlfrx7quYbOPsB8ijKleX99A5V003kloB_9c7EyUzdA6BcPYaz90Bjpt-ujsCNfjzkACtZONiYnYyehSK0AZoeuVNzIYDb0LWzhYqJ780Cdq63RvxmSFqf8WvLKyDebdab8EP26W68Vddv_1tl5c3WeK0ZxkJeMEc0stahSnRUUqQnJW5UYpU_ACsYZyWmpkC8SVxjpniiKkkyAtUpjTS_DxeO_OD7_2JkTRuaBM28reDPsgCl4xzkuSwOoIKj-E4I0VO-866UeBkZjiEBsxTV1MUxdTHOI5DnFI6vvTG_umM_qfeJp_Aj6cABmUbK2XvXLhzBFUVSm_MnGfj9xv15rxvz8grh-W0yn52dF3IZrD2Zd-K4qSlrn4uboVq9W3L9_JAxV39C8B2LSI</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>69849972</pqid></control><display><type>article</type><title>The NCEP-ATPIII but not the IDF criteria for the metabolic syndrome identify Type 2 diabetic patients at increased risk of chronic kidney disease</title><source>Wiley-Blackwell Read & Publish Collection</source><creator>Luk, A. O. Y. ; Ma, R. C. W. ; So, W-Y. ; Yang, X-L. ; Kong, A. P. S. ; Ozaki, R. ; Ko, G. T. C. ; Chow, C-C. ; Cockram, C. S. ; Chan, J. C. N. ; Tong, P. C. Y.</creator><creatorcontrib>Luk, A. O. Y. ; Ma, R. C. W. ; So, W-Y. ; Yang, X-L. ; Kong, A. P. S. ; Ozaki, R. ; Ko, G. T. C. ; Chow, C-C. ; Cockram, C. S. ; Chan, J. C. N. ; Tong, P. C. Y.</creatorcontrib><description>Aim To examine the association between chronic kidney disease (CKD) and the metabolic syndrome (MetS) using both International Diabetes Federation (IDF) and National Cholesterol Education Program's Adult Treatment Panel III (NCEP‐ATPIII) definitions in Chinese subjects with Type 2 diabetes.
Methods Subjects with Type 2 diabetes were categorized according to the presence or absence of MetS by IDF or NCEP‐ATPIII criteria. CKD was considered present if glomerular filtration rate, calculated using the abbreviated equation developed by the Modification of Diet in Renal Disease study with Chinese modification, was < 60 ml/min per 1.73 m2. Multivariate logistic regression analysis of the association between CKD and MetS by either definition was performed.
Results Of 6350 subjects (mean age 55.1 ± 13.3 years), 3439 (54.2%) and 3204 (50.5%) had MetS by IDF and NCEP‐ATPIII definitions, respectively. Using the IDF definition, the presence of MetS was not associated with CKD [odds ratio (OR) 0.96, 95% confidence interval (CI) 0.71, 1.29, P = 0.784]. In contrast, the association with CKD was significant when MetS was defined by the NCEP‐ATPIII definition (OR 1.75, 95% CI 1.37, 2.24, P < 0.001). In subjects who did not have MetS (n = 2911) as defined by IDF criteria, 997 fulfilled the MetS criteria of NCEP‐ATP III. The association with CKD was stronger, after adjustment for covariates, in these subjects (OR 1.42, 95% CI 1.03, 1.97, P = 0.032) compared with subjects who met IDF criteria of MetS.
Conclusion In Type 2 diabetes, NCEP‐ATPIII, but not the IDF definition of MetS, identifies a subgroup of patients who have a higher risk of CKD.</description><identifier>ISSN: 0742-3071</identifier><identifier>EISSN: 1464-5491</identifier><identifier>DOI: 10.1111/j.1464-5491.2008.02602.x</identifier><identifier>PMID: 19046240</identifier><identifier>CODEN: DIMEEV</identifier><language>eng</language><publisher>Oxford, UK: Blackwell Publishing Ltd</publisher><subject>Adult ; Aged ; Biological and medical sciences ; chronic kidney disease ; Diabetes Mellitus, Type 2 - complications ; Diabetes Mellitus, Type 2 - diagnosis ; Diabetes Mellitus, Type 2 - physiopathology ; Diabetes. Impaired glucose tolerance ; Endocrine pancreas. Apud cells (diseases) ; Endocrinopathies ; Etiopathogenesis. Screening. Investigations. Target tissue resistance ; Feeding. Feeding behavior ; Fundamental and applied biological sciences. Psychology ; Glomerular Filtration Rate ; Humans ; Kidney Failure, Chronic - complications ; Kidney Failure, Chronic - diagnosis ; Kidney Failure, Chronic - physiopathology ; Medical sciences ; metabolic syndrome ; Metabolic Syndrome - complications ; Metabolic Syndrome - diagnosis ; Metabolic Syndrome - physiopathology ; Middle Aged ; Risk Factors ; Type 2 diabetes mellitus ; Vertebrates: anatomy and physiology, studies on body, several organs or systems ; Vertebrates: endocrinology</subject><ispartof>Diabetic medicine, 2008-12, Vol.25 (12), p.1419-1425</ispartof><rights>2008 The Authors. Journal compilation © 2008 Diabetes UK</rights><rights>2009 INIST-CNRS</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c4352-749219f3f0bc936828225485ecce69604b3937d0f609cd1d54c300df3faf0c193</citedby><cites>FETCH-LOGICAL-c4352-749219f3f0bc936828225485ecce69604b3937d0f609cd1d54c300df3faf0c193</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=20883077$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/19046240$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Luk, A. O. Y.</creatorcontrib><creatorcontrib>Ma, R. C. W.</creatorcontrib><creatorcontrib>So, W-Y.</creatorcontrib><creatorcontrib>Yang, X-L.</creatorcontrib><creatorcontrib>Kong, A. P. S.</creatorcontrib><creatorcontrib>Ozaki, R.</creatorcontrib><creatorcontrib>Ko, G. T. C.</creatorcontrib><creatorcontrib>Chow, C-C.</creatorcontrib><creatorcontrib>Cockram, C. S.</creatorcontrib><creatorcontrib>Chan, J. C. N.</creatorcontrib><creatorcontrib>Tong, P. C. Y.</creatorcontrib><title>The NCEP-ATPIII but not the IDF criteria for the metabolic syndrome identify Type 2 diabetic patients at increased risk of chronic kidney disease</title><title>Diabetic medicine</title><addtitle>Diabet Med</addtitle><description>Aim To examine the association between chronic kidney disease (CKD) and the metabolic syndrome (MetS) using both International Diabetes Federation (IDF) and National Cholesterol Education Program's Adult Treatment Panel III (NCEP‐ATPIII) definitions in Chinese subjects with Type 2 diabetes.
Methods Subjects with Type 2 diabetes were categorized according to the presence or absence of MetS by IDF or NCEP‐ATPIII criteria. CKD was considered present if glomerular filtration rate, calculated using the abbreviated equation developed by the Modification of Diet in Renal Disease study with Chinese modification, was < 60 ml/min per 1.73 m2. Multivariate logistic regression analysis of the association between CKD and MetS by either definition was performed.
Results Of 6350 subjects (mean age 55.1 ± 13.3 years), 3439 (54.2%) and 3204 (50.5%) had MetS by IDF and NCEP‐ATPIII definitions, respectively. Using the IDF definition, the presence of MetS was not associated with CKD [odds ratio (OR) 0.96, 95% confidence interval (CI) 0.71, 1.29, P = 0.784]. In contrast, the association with CKD was significant when MetS was defined by the NCEP‐ATPIII definition (OR 1.75, 95% CI 1.37, 2.24, P < 0.001). In subjects who did not have MetS (n = 2911) as defined by IDF criteria, 997 fulfilled the MetS criteria of NCEP‐ATP III. The association with CKD was stronger, after adjustment for covariates, in these subjects (OR 1.42, 95% CI 1.03, 1.97, P = 0.032) compared with subjects who met IDF criteria of MetS.
Conclusion In Type 2 diabetes, NCEP‐ATPIII, but not the IDF definition of MetS, identifies a subgroup of patients who have a higher risk of CKD.</description><subject>Adult</subject><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>chronic kidney disease</subject><subject>Diabetes Mellitus, Type 2 - complications</subject><subject>Diabetes Mellitus, Type 2 - diagnosis</subject><subject>Diabetes Mellitus, Type 2 - physiopathology</subject><subject>Diabetes. Impaired glucose tolerance</subject><subject>Endocrine pancreas. Apud cells (diseases)</subject><subject>Endocrinopathies</subject><subject>Etiopathogenesis. Screening. Investigations. Target tissue resistance</subject><subject>Feeding. Feeding behavior</subject><subject>Fundamental and applied biological sciences. Psychology</subject><subject>Glomerular Filtration Rate</subject><subject>Humans</subject><subject>Kidney Failure, Chronic - complications</subject><subject>Kidney Failure, Chronic - diagnosis</subject><subject>Kidney Failure, Chronic - physiopathology</subject><subject>Medical sciences</subject><subject>metabolic syndrome</subject><subject>Metabolic Syndrome - complications</subject><subject>Metabolic Syndrome - diagnosis</subject><subject>Metabolic Syndrome - physiopathology</subject><subject>Middle Aged</subject><subject>Risk Factors</subject><subject>Type 2 diabetes mellitus</subject><subject>Vertebrates: anatomy and physiology, studies on body, several organs or systems</subject><subject>Vertebrates: endocrinology</subject><issn>0742-3071</issn><issn>1464-5491</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2008</creationdate><recordtype>article</recordtype><recordid>eNqNkctuEzEUhi0EoqHwCsgb2E3wbS5esKjStB3RhiKCWFoeX1Qncwm2IzKPwRvjaaKwxRtb53yfbZ0fAIjRHKf1aTPHrGBZzjieE4SqOSIFIvPDCzA7N16CGSoZySgq8QV4E8IGIUw45a_BBeaIFYShGfizfjJwtVg-Zlfrx7quYbOPsB8ijKleX99A5V003kloB_9c7EyUzdA6BcPYaz90Bjpt-ujsCNfjzkACtZONiYnYyehSK0AZoeuVNzIYDb0LWzhYqJ780Cdq63RvxmSFqf8WvLKyDebdab8EP26W68Vddv_1tl5c3WeK0ZxkJeMEc0stahSnRUUqQnJW5UYpU_ACsYZyWmpkC8SVxjpniiKkkyAtUpjTS_DxeO_OD7_2JkTRuaBM28reDPsgCl4xzkuSwOoIKj-E4I0VO-866UeBkZjiEBsxTV1MUxdTHOI5DnFI6vvTG_umM_qfeJp_Aj6cABmUbK2XvXLhzBFUVSm_MnGfj9xv15rxvz8grh-W0yn52dF3IZrD2Zd-K4qSlrn4uboVq9W3L9_JAxV39C8B2LSI</recordid><startdate>200812</startdate><enddate>200812</enddate><creator>Luk, A. O. Y.</creator><creator>Ma, R. C. W.</creator><creator>So, W-Y.</creator><creator>Yang, X-L.</creator><creator>Kong, A. P. S.</creator><creator>Ozaki, R.</creator><creator>Ko, G. T. C.</creator><creator>Chow, C-C.</creator><creator>Cockram, C. S.</creator><creator>Chan, J. C. N.</creator><creator>Tong, P. C. Y.</creator><general>Blackwell Publishing Ltd</general><general>Blackwell</general><scope>BSCLL</scope><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>7X8</scope></search><sort><creationdate>200812</creationdate><title>The NCEP-ATPIII but not the IDF criteria for the metabolic syndrome identify Type 2 diabetic patients at increased risk of chronic kidney disease</title><author>Luk, A. O. Y. ; Ma, R. C. W. ; So, W-Y. ; Yang, X-L. ; Kong, A. P. S. ; Ozaki, R. ; Ko, G. T. C. ; Chow, C-C. ; Cockram, C. S. ; Chan, J. C. N. ; Tong, P. C. Y.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c4352-749219f3f0bc936828225485ecce69604b3937d0f609cd1d54c300df3faf0c193</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2008</creationdate><topic>Adult</topic><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>chronic kidney disease</topic><topic>Diabetes Mellitus, Type 2 - complications</topic><topic>Diabetes Mellitus, Type 2 - diagnosis</topic><topic>Diabetes Mellitus, Type 2 - physiopathology</topic><topic>Diabetes. Impaired glucose tolerance</topic><topic>Endocrine pancreas. Apud cells (diseases)</topic><topic>Endocrinopathies</topic><topic>Etiopathogenesis. Screening. Investigations. Target tissue resistance</topic><topic>Feeding. Feeding behavior</topic><topic>Fundamental and applied biological sciences. Psychology</topic><topic>Glomerular Filtration Rate</topic><topic>Humans</topic><topic>Kidney Failure, Chronic - complications</topic><topic>Kidney Failure, Chronic - diagnosis</topic><topic>Kidney Failure, Chronic - physiopathology</topic><topic>Medical sciences</topic><topic>metabolic syndrome</topic><topic>Metabolic Syndrome - complications</topic><topic>Metabolic Syndrome - diagnosis</topic><topic>Metabolic Syndrome - physiopathology</topic><topic>Middle Aged</topic><topic>Risk Factors</topic><topic>Type 2 diabetes mellitus</topic><topic>Vertebrates: anatomy and physiology, studies on body, several organs or systems</topic><topic>Vertebrates: endocrinology</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Luk, A. O. Y.</creatorcontrib><creatorcontrib>Ma, R. C. W.</creatorcontrib><creatorcontrib>So, W-Y.</creatorcontrib><creatorcontrib>Yang, X-L.</creatorcontrib><creatorcontrib>Kong, A. P. S.</creatorcontrib><creatorcontrib>Ozaki, R.</creatorcontrib><creatorcontrib>Ko, G. T. C.</creatorcontrib><creatorcontrib>Chow, C-C.</creatorcontrib><creatorcontrib>Cockram, C. S.</creatorcontrib><creatorcontrib>Chan, J. C. N.</creatorcontrib><creatorcontrib>Tong, P. C. Y.</creatorcontrib><collection>Istex</collection><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>MEDLINE - Academic</collection><jtitle>Diabetic medicine</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Luk, A. O. Y.</au><au>Ma, R. C. W.</au><au>So, W-Y.</au><au>Yang, X-L.</au><au>Kong, A. P. S.</au><au>Ozaki, R.</au><au>Ko, G. T. C.</au><au>Chow, C-C.</au><au>Cockram, C. S.</au><au>Chan, J. C. N.</au><au>Tong, P. C. Y.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>The NCEP-ATPIII but not the IDF criteria for the metabolic syndrome identify Type 2 diabetic patients at increased risk of chronic kidney disease</atitle><jtitle>Diabetic medicine</jtitle><addtitle>Diabet Med</addtitle><date>2008-12</date><risdate>2008</risdate><volume>25</volume><issue>12</issue><spage>1419</spage><epage>1425</epage><pages>1419-1425</pages><issn>0742-3071</issn><eissn>1464-5491</eissn><coden>DIMEEV</coden><abstract>Aim To examine the association between chronic kidney disease (CKD) and the metabolic syndrome (MetS) using both International Diabetes Federation (IDF) and National Cholesterol Education Program's Adult Treatment Panel III (NCEP‐ATPIII) definitions in Chinese subjects with Type 2 diabetes.
Methods Subjects with Type 2 diabetes were categorized according to the presence or absence of MetS by IDF or NCEP‐ATPIII criteria. CKD was considered present if glomerular filtration rate, calculated using the abbreviated equation developed by the Modification of Diet in Renal Disease study with Chinese modification, was < 60 ml/min per 1.73 m2. Multivariate logistic regression analysis of the association between CKD and MetS by either definition was performed.
Results Of 6350 subjects (mean age 55.1 ± 13.3 years), 3439 (54.2%) and 3204 (50.5%) had MetS by IDF and NCEP‐ATPIII definitions, respectively. Using the IDF definition, the presence of MetS was not associated with CKD [odds ratio (OR) 0.96, 95% confidence interval (CI) 0.71, 1.29, P = 0.784]. In contrast, the association with CKD was significant when MetS was defined by the NCEP‐ATPIII definition (OR 1.75, 95% CI 1.37, 2.24, P < 0.001). In subjects who did not have MetS (n = 2911) as defined by IDF criteria, 997 fulfilled the MetS criteria of NCEP‐ATP III. The association with CKD was stronger, after adjustment for covariates, in these subjects (OR 1.42, 95% CI 1.03, 1.97, P = 0.032) compared with subjects who met IDF criteria of MetS.
Conclusion In Type 2 diabetes, NCEP‐ATPIII, but not the IDF definition of MetS, identifies a subgroup of patients who have a higher risk of CKD.</abstract><cop>Oxford, UK</cop><pub>Blackwell Publishing Ltd</pub><pmid>19046240</pmid><doi>10.1111/j.1464-5491.2008.02602.x</doi><tpages>7</tpages></addata></record> |
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| subjects | Adult Aged Biological and medical sciences chronic kidney disease Diabetes Mellitus, Type 2 - complications Diabetes Mellitus, Type 2 - diagnosis Diabetes Mellitus, Type 2 - physiopathology Diabetes. Impaired glucose tolerance Endocrine pancreas. Apud cells (diseases) Endocrinopathies Etiopathogenesis. Screening. Investigations. Target tissue resistance Feeding. Feeding behavior Fundamental and applied biological sciences. Psychology Glomerular Filtration Rate Humans Kidney Failure, Chronic - complications Kidney Failure, Chronic - diagnosis Kidney Failure, Chronic - physiopathology Medical sciences metabolic syndrome Metabolic Syndrome - complications Metabolic Syndrome - diagnosis Metabolic Syndrome - physiopathology Middle Aged Risk Factors Type 2 diabetes mellitus Vertebrates: anatomy and physiology, studies on body, several organs or systems Vertebrates: endocrinology |
| title | The NCEP-ATPIII but not the IDF criteria for the metabolic syndrome identify Type 2 diabetic patients at increased risk of chronic kidney disease |
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