Allergic bronchopulmonary aspergillosis with multiple Streptococcus pneumoniae lung abscesses: An unusual initial case presentation

Allergic bronchopulmonary aspergillosis (ABPA) is a disease affecting asthmatic subjects with variability in its clinical presentation. Symptoms typically consist of cough producing golden-brown mucous plugs and occasionally include fever or malaise, although patients may be asymptomatic. Radiologic...

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Bibliographic Details
Published in:Journal of allergy and clinical immunology 1999-07, Vol.104 (1), p.238-240
Main Authors: Ricaurté, Kimberly K., Greenberger, Paul A., Fullerton, David A.
Format: Article
Language:English
Subjects:
Abscess - complications
Abscess - diagnosis
Abscess - diagnostic imaging
Adult
Aspergillosis, Allergic Bronchopulmonary - complications
Aspergillosis, Allergic Bronchopulmonary - diagnosis
Aspergillosis, Allergic Bronchopulmonary - diagnostic imaging
Aspergillus
Biological and medical sciences
Diagnosis, Differential
Female
Human mycoses
Humans
Infectious diseases
Lung Diseases - complications
Lung Diseases - diagnosis
Lung Diseases - diagnostic imaging
Medical sciences
Mycoses
Mycoses of the respiratory system
Pneumococcal Infections - complications
Pneumococcal Infections - diagnosis
Pneumococcal Infections - diagnostic imaging
Radiography
Streptococcus pneumoniae
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Description
Summary:Allergic bronchopulmonary aspergillosis (ABPA) is a disease affecting asthmatic subjects with variability in its clinical presentation. Symptoms typically consist of cough producing golden-brown mucous plugs and occasionally include fever or malaise, although patients may be asymptomatic. Radiologic studies commonly reveal pulmonary infiltrates or central bronchiectasis, and peripheral blood eosinophilia may be present in the absence of systemic corticosteroid use. Confirmation of the diagnosis requires identifying immediate cutaneous reactivity to Aspergillus spp and serologic evidence of elevation of total serum IgE (>1000 ng/mL), elevation of serum IgE and IgG antibodies to Aspergillus fumigatus, and the presence of precipitating antibodies to A fumigatus. We report the case of a patient who was first seen with bilateral lung abscesses and underlying ABPA.
ISSN:0091-6749
1097-6825
DOI:10.1016/S0091-6749(99)70142-9