Infectious complications of combination anticancer chemotherapy for urogenital cancers

We reviewed the infectious complications in 207 courses of anticancer chemotherapy to 93 patients with urogenital cancer. Thirty episodes (14.5%) of neutropenic fever containing 9 cases (4.3%) of infection were observed. Five patients (16.7%) had pyelonephritis, one (3.3%) had acute prostatitis, two...

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Bibliographic Details
Published in:International urology and nephrology 1999, Vol.31 (1), p.7-14
Main Authors: Matsumoto, T, Takahashi, K, Tanaka, M, Kumazawa, J
Format: Article
Language:English
Subjects:
Adult
Aged
Antineoplastic Combined Chemotherapy Protocols - therapeutic use
Carcinoma, Renal Cell - drug therapy
Carcinoma, Transitional Cell - drug therapy
Female
Fever of Unknown Origin - etiology
Humans
Hydronephrosis - complications
Infection - etiology
Kidney Neoplasms - drug therapy
Male
Middle Aged
Multivariate Analysis
Neutropenia - etiology
Prostatic Neoplasms - drug therapy
Pyelonephritis - etiology
Testicular Neoplasms - drug therapy
Urinary Diversion
Urogenital Neoplasms - drug therapy
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Summary:We reviewed the infectious complications in 207 courses of anticancer chemotherapy to 93 patients with urogenital cancer. Thirty episodes (14.5%) of neutropenic fever containing 9 cases (4.3%) of infection were observed. Five patients (16.7%) had pyelonephritis, one (3.3%) had acute prostatitis, two (6.6%) had pneumonia and one (3.3%) had bacteraemia. Multivariate analysis revealed that the infectious complications during anticancer chemotherapy were mainly associated with urinary diversion, hydronephrosis and duration of severe neutropenia (
ISSN:0301-1623
1573-2584
DOI:10.1023/A:1007107403610