Greater fat oxidation with diacylglycerol oil consumption for 14 days compared with triacylglycerol oil consumption in overweight men and women

• Published in: International Journal of Obesity 2008-12, Vol.32 (12), p.1841-1847
• Main Authors: Hibi, M, Takase, H, Yasunaga, K, Yamaguchi, T, Shiiba, D, Saito, S, Yokoyama, R, Kudo, N, Katsuragi, Y, Meguro, S, Shimizu, A, Tokimitsu, I
• Format: Article
• Language: English
• Subjects: Acclimatization; Adipose Tissue - drug effects; Adult; alpha-Linolenic Acid - pharmacology; Biological and medical sciences; Body weight; Breath Tests; Canola Oil; Carbon dioxide; Carbon Dioxide - chemistry; Consumption; Cross-Over Studies; diacylglycerols; Diet; Dietary fat; Dietary Fats - metabolism; Diglycerides - administration & dosage; Diglycerides - pharmacology; Double-Blind Method; energy metabolism; Energy Metabolism - drug effects; Epidemiology; experimental diets; fat intake; Fat metabolism; Fatty Acids, Monounsaturated; Female; Females; Food; Genetic aspects; Health aspects; Health Promotion and Disease Prevention; Humans; Ingestion; Internal Medicine; lipid peroxidation; Male; Males; Medical sciences; Medicine; Medicine & Public Health; men; Metabolic Diseases; Middle Aged; Obesity; Oils & fats; original-article; overweight; Overweight - metabolism; Overweight persons; Oxidation; Oxidation-Reduction; Plant Oils - administration & dosage; Plant Oils - pharmacology; Public Health; resting metabolic rate; Safflower Oil - pharmacology; Soybean Oil - pharmacology; Substrates; Tokyo; triacylglycerols; Triglycerides - administration & dosage; Triglycerides - pharmacology; women
• ISSN: 0307-0565; 1476-5497
• DOI: 10.1038/ijo.2008.197

Background: Several studies have reported increased fat oxidation with diacylglycerol (DAG) oil consumption. However, the effects of long-term DAG oil consumption on energy metabolism remain to be investigated. Objective: The objective of this study was to compare the effects of 14 days of either DAG or triacylglycerol (TAG) oil consumption on substrate oxidation, energy expenditure (EE) and dietary fat oxidation. Design: Eight males and six females participated in this randomized, double-blind, crossover feeding study. Each patient consumed the 14-day controlled test diet containing either 10 g day-1 of DAG or TAG oil for acclimatization before a respiratory chamber measurement, followed by a 2-week washout period between diet treatments. Substrate oxidation and EE were measured in the respiratory chamber at the end of each dietary treatment. The patients consumed test oil as 15% of total caloric intake in the respiratory chamber (mean test oil intake was 36.1+/-6.6 g day-1). Results: Twenty-four hour fat oxidation was significantly greater with 14 days of DAG oil consumption compared with TAG oil consumption (78.6+/-19.6 and 72.6+/-14.9 g day-1, respectively, P